Case Report of Clinically Probable Sporadic Creutzfeldt - Jakob Disease from A Tertiary Care Hospital in South India

We are reporting an otherwise healthy lady of forty eight years suffering from rapidly progressive dementia, behavioural disturbances, myoclonus, ataxia and extrapyramidal features of eight months duration with characteristic abnormalities on brain imaging, electroencephalography with positive cerebrospinal fluid 14-3-3 protein, satisfying the revised World Health organization (WHO) criteria for diagnosis of “clinically probable Sporadic Creutzfeldt-Jakob disease (sCJD)”. An attempt was made to clinically differentiate the diagnostic possibilities.