Evidence of reinfection in CD4+ T lymphocyte depleted FL-RhCMVΔRh13.1/SIV<i>gag</i> inoculated dams.
- Matilda J. Moström (7478972)
- Shan Yu (219591)
- Dollnovan Tran (7478975)
- Frances M. Saccoccio (17101598)
- Cyril J. Versoza (17101601)
- Daniel Malouli (340369)
- Anne Mirza (17101604)
- Sarah Valencia (16067315)
- Margaret Gilbert (15016470)
- Robert V. Blair (11722847)
- Scott Hansen (522616)
- Peter Barry (7860296)
- Klaus Früh (106067)
- Jeffrey D. Jensen (8029058)
- Susanne P. Pfeifer (3250662)
- Timothy F. Kowalik (9681989)
- Sallie R. Permar (7310132)
- Amitinder Kaur (228367)
Publication date
October 2023
DOIAbstract
(A) RhCMV-specific (black line) and SIVgag-specific (grey line) real time PCR results in the saliva of one CMV-seropositive reinfected animal (KB91). All other animals were found negative for SIVgag DNA in saliva and urine. (B) Detection of SIV Gag-specific T lymphocyte responses measured longitudinally against a SIVmac239 Gag peptide pool in CMV-seropositive reinfected macaques (KB91, KK24, and JP01) inoculated with RhCMV UCD52 and FL-RhCMVΔRh13.1/SIVgag. Horizontal stippled line shows negative cut-off based on pre-reinfection values.</p
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