Electrochemical Synthesis of <i>S-</i>Aryl Dibenzothiophenium Triflates as Precursors for Selective Nucleophilic Aromatic (Radio)fluorination

A novel electrosynthetic approach to aryl dibenzothiophenium salts, including the direct intramolecular formation of a C–S bond in a metal-free, electrochemical key step under ambient conditions, is reported. The broad applicability of this method is demonstrated with 14 examples, including nitrogen-containing heterocycles in isolated yields up to 72%. The resulting sulfonium salts can be used as precursors for fluorine labeling to give [18F]fluoroarenes as found in PET tracer ligands