Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations
- Mariotti, Benedetta
- Meconi, Federico
- Palmieri, Raffaele
- De Bellis, Eleonora
- Lavorgna, Serena
- Ottone, Tiziana
- Martini, Vincenza
- Lo-Coco, Francesco
- Cicconi, Laura
DOIAbstract
We present a case report of a patient with acute myeloid leukemia (AML) characterized by the simultaneous presence of nucleophosmin 1 (NPM1) mutation and the breakpoint cluster region-Abelson (BCR-ABL) fusion oncogene. Our findings emphasize the importance of routinely including BCR-ABL in the diagnostic workup of AML in order to offer to the patients the most appropriate risk category and treatment options
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