Purpose: Sinonasal tumours are rare diseases with poor prognosis. Multimodal approach including surgery is widely used, although no standard therapy has been established in prospective trials. This study assessed activity and safety of an innovative integration of multimodality treatment-induction chemotherapy (ICT), surgery and radiotherapy (RT)-modulated by histology and response to ICT. Methods: Patients with untreated, operable sinonasal tumours with selected histotypes (squamous cell carcinoma, intestinal-type adenocarcinoma, sinonasal undifferentiated and neuroendocrine carcinoma, olfactory neuroblastoma) were enrolled in a single-arm, phase II, multicenter clinical trial. Patients were treated with up to 5 ICT cycles, whose regimen w...
Background: Radiotherapy has a central role in the treatment of sinonasal malignancies, either as po...
Purpose: Treatment of sinonasal malignant tumors is challenging, and evidence to establish a standar...
OBJECTIVE: To investigate different treatment strategies for primary early-stage (pT1-T2) sinonasal ...
Purpose: Sinonasal tumours are rare diseases with poor prognosis. Multimodal approach including surg...
Purpose: Unresectable, locally advanced sinonasal epithelial tumours are rare diseases with poor pro...
Purpose: We report the outcome of a mono-institutional retrospective study of sinonasal carcinoma wi...
BACKGROUND AND PURPOSE: \nTo evaluate the safety and efficacy of carbon ion radiotherapy (CIRT) for ...
Purpose: Due to the rarity and the variety of histological types of sinonasal cancers, there is a pa...
AIMS: Sinonasal malignancies are rare; the most common histological subtype is squamous cell carcino...
Background: The aim of this study was to evaluate the disease outcomes of patients treated with defi...
Purpose: Sinonasal malignancies (SNM) represent a rare and complex group of cancers that includes a ...
PURPOSE OF REVIEW: The present review provides the reader with the state-of-the-art concepts of sino...
Objective: Outcomes of locally advanced epithelial sinonasal cancers remain unsatisfactory; moreover...
AimsSinonasal malignancies are rare; the most common histological subtype is squamous cell carcinoma...
Background: Radiotherapy has a central role in the treatment of sinonasal malignancies, either as po...
Purpose: Treatment of sinonasal malignant tumors is challenging, and evidence to establish a standar...
OBJECTIVE: To investigate different treatment strategies for primary early-stage (pT1-T2) sinonasal ...
Purpose: Sinonasal tumours are rare diseases with poor prognosis. Multimodal approach including surg...
Purpose: Unresectable, locally advanced sinonasal epithelial tumours are rare diseases with poor pro...
Purpose: We report the outcome of a mono-institutional retrospective study of sinonasal carcinoma wi...
BACKGROUND AND PURPOSE: \nTo evaluate the safety and efficacy of carbon ion radiotherapy (CIRT) for ...
Purpose: Due to the rarity and the variety of histological types of sinonasal cancers, there is a pa...
AIMS: Sinonasal malignancies are rare; the most common histological subtype is squamous cell carcino...
Background: The aim of this study was to evaluate the disease outcomes of patients treated with defi...
Purpose: Sinonasal malignancies (SNM) represent a rare and complex group of cancers that includes a ...
PURPOSE OF REVIEW: The present review provides the reader with the state-of-the-art concepts of sino...
Objective: Outcomes of locally advanced epithelial sinonasal cancers remain unsatisfactory; moreover...
AimsSinonasal malignancies are rare; the most common histological subtype is squamous cell carcinoma...
Background: Radiotherapy has a central role in the treatment of sinonasal malignancies, either as po...
Purpose: Treatment of sinonasal malignant tumors is challenging, and evidence to establish a standar...
OBJECTIVE: To investigate different treatment strategies for primary early-stage (pT1-T2) sinonasal ...