Responsivity of Negative Symptoms to Typical Neuroleptic Drugsin Schizophrenia

The psychopharmacological management of schizophrenia consists primarily of neuroleptics. These drugs have successfully changed the scenario of psychiatry since the 1950s. They have mainly been used for controlling positive symptoms in schizophrenia, but on closer look it is evident that positive and negative symptoms both respond to neuroleptics in the acute and chronic stages of schizophrenia separate reports are cited for acute and chronic stages with an aim to quantitate the response. The early as well as recent studies support these obervations with few exceptions. However, greater responsivity has been observed in the acute stages of schizophrenia