Bone tissue reparation and regeneration using bioactive material in endodontic surgery – a case report

Posljednjih godina u kliničkoj primjeni dentalnih materijala dogodila se značajna evolucija. Bioaktivni materijali potiču cijeljenje pulpnog i periapikalnog tkiva te ostvaruju interaktivni učinak sa stanicama i tkivima. Iz toga proizlazi široko indikacijsko područje i raznolikost primjene kroz restaurativni i regenerativni rezultat terapije u različitim specijalističkim granama dentalne medicine. U ovom prikazu kliničkog slučaja provedena je apikotomija zuba 21 uz enukleaciju tvorbe, uzimanje uzorka za patohistološku analizu, izradu retrogradnog kaviteta i primjenu bioaktivnog materijala. Retrogradni kavitet je izrađen piezoelektričnim ultrazvučnim nastavkom i zatvoren Biodentinom (Septodont, Saint-Maur-des Fosses, Francuska). Mukoperiostalni režanj je reponiran i zašiven. Radiološki kontrolni pregled proveden je nakon šest mjeseci te nakon godinu dana u svrhu praćenja dinamike cijeljenja koštanog defekta. Cijeljenje lezije uočljivo je već nakon šest mjeseci. Zbog svoje biološke sigurnosti i induktivnoga biološkog učinka te širokoga indikacijskog područja primjene, bioaktivni dentalni materijali fiziološki nadomještaju oštećenu zubnu strukturu, induciraju regeneraciju periapikalnih upalnih lezija te revaskularizaciju i revitalizaciju tkiva.In recent years, a significant evolution has taken place in the clinical application of dental materials. Bioactive materials promote pulpal and periapical tissue healing and induce an interactive effect with cells and tissues. This results in a wide range of indications and a variety of applications through the restorative and regenerative results of therapy in various specialist branches of dental medicine. In this presentation of the clinical case, an apicotomy of tooth 21 was performed with enucleation of the formation, taking a sample for pathohistological analysis, making a retrograde cavity and applying bioactive material. The retrograde cavity was created with a piezoelectric ultrasound attachment and closed with Biodentin (Septodont, Saint-Maur-des Fosses, France). The mucoperiosteal flap was repositioned and sutured. A radiological control examination was carried out after six months and after one year in order to monitor the dynamics of bone defect healing. The healing of the lesion was already noticeable after six months. Due to their biological safety, inductive biological effect, and wide indication area of application, bioactive dental materials physiologically replace the damaged tooth structure, induce regeneration of periapical inflammatory lesions and tissue revascularization and revitalization