Hepatocutaneous syndrome in dogs

Hepatokutani sindrom u pasa rijedak je metabolički poremećaj koji uključuje površinski nekrolitični dermatitis, hepatopatiju povezanu s hepatokutanim sindromom, hipoaminoacidemiju i aminoaciduriju. U nekih se pasa kožne lezije mogu pojaviti kasnije, stoga je u literaturi predložen novi naziv, sindrom aminoacidurične pseće hipoaminoacidemične hepatopatije, koji bi uključivao pse s kožnim lezijama i bez njih. U ovom je radu opisan patoanatomski i patohistološki nalaz hepatokutanog sindroma psa starog 10 godina, pasmine malteški psić, obduciranog u Zavodu za Veterinarsku patologiju Veterinarskog fakulteta Sveučilišta u ZagrebuHepatocutaneous syndrome is a rare metabolic disorder in dogs, defined by the presence of superficial necrolytic dermatitis, hepatocutaneous-associated hepatopathy, aminoaciduria and hypoaminoacidemia. Since in some dogs cutaneous lesions can manifest in later stages of the disease, an alternative term was proposed: aminoaciduric canine hypoaminoacidemic hepatopathy syndrome (ACHES), which includes dogs with and without developed skin lesions. This article presents the gross and histopathological findings of hepatocutaneous syndrome in a 10 year old male Maltese dog necropsied at the Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Zagreb