Design and development of a bioreactor with jacketed heating and cooling

V zaključni nalogi smo obravnavamo bioreaktorske sisteme, različne načine ogrevanja in hlajenja ter predlagali konfiguracijo sistema za obravnavan primer. Po pregledu literature o bioreaktorskih sistemih, njihovih principih delovanja in principih prenosa toplote in snovi smo določili ustrezno opremo, ki je nujna za njihovo optimalno delovanje. Postopek odločanja je temeljil na poglobljenem razumevanju dejavnikov, ki vplivajo na učinkovitost prenosa toplote in snovi, vključno s kritičnimi vidiki mešanja in integracijo pregrad, zato smo kot najprimernejšo izbrali rešitev ogrevanja in hlajenja s plaščem. Predstavili smo rezultate zasnove in razvoja biorekatorja s ustreznimi funkcionalnimi diagrami.In the final thesis we discuss the bioreactor system, the different heating and cooling methods and selecting the most suitable configuration for our case. After an extensive review of the existing literature on bioreactor systems, their operating principles and heat transfer principles, we have identified the appropriate equipment required for their optimal operation. Our decision-making process was based on an in-depth understanding of the factors that influence heat and mass transfer efficiency, including critical aspects of mixing and strategic integration of the barriers, and we selected the jacketed solution as the most appropriate. We presented the results of the design and development of the bioreactor with corresponding functional diagrams