The Variability of Psychophysical Parameters following Surface and Subdermal Stimulation:A Multiday Study in Amputees

Electrotactile stimulation has been suggested as a modality for providing sensory feedback in upper limb prostheses.This study investigates the multiday variability of subdermal and surface stimulation. Electrical stimulation was delivered using either surface or fine wire electrodes placed right under the skin in eight amputees for seven consecutive days. The variability of psychophysical measurements, including detection threshold(DT), pain threshold (PT), dynamic range (DR), just noticeable difference (JND), Weber fraction (WF) and quality of evoked sensations, was evaluated using the coefficient of variation (CoV).In addition, the systematic change in the mean of the parameters across days was assessed in both stimulation modalities. In the caseof DT, PT, DR, and perceived intensity at 100 Hz, the CoV ofsurface stimulation was significantly smaller than that of subdermal stimulation. Only PT showed a significant systematic change in the mean value across days for both modalities. Theoutcome of this study has implications for the choice of modality in delivering sensory feedback, though the significance of the quantified variability needs to be evaluated using usability tests with user feedback