This bachelor thesis aims to study the selected parameters and nutrients of water quality in relation to the rainfall-runoff regime in the Sázavka River basin. The rainfall-runoff regime is influenced by many factors, including the climate change, which has received more and more attention in recent years. These changes may have a consequential impact on the quality of surface waters. In the first part of this paper selected parameters of water quality are presented. The aim was to try to understand their behaviour under the changing water flow dynamics. For this purpose, Czech and foreign literature was used. In this thesis there are also presented the most common statistical methods that are used in analysing geochemical parameters. The s...