Additional file 2: Fig. S2. Dose effect of CTGF and mouse pulmonary fibrosis. (A) Masson staining was observed in lung tissue after 7 days of continuous administration of 20 ug/kg CTGF, no obvious fiber staining was found in lung tissue. (B) After continuous administration of 100 ug/kg CTGF for 7 days, there was a small amount of fiber deposition in the alveolar septum (black arrow indicates fiber deposition). (C) Significant pulmonary fibrosis was observed after 7 days of continuous administration of 200ug/kg CTGF. Scale bar, 200 μ
Alveolar type II (ATII) cell proliferation and differentiation are important mechanisms in repair fo...
Blockade of IL-6 at early inflammatory stage of BLM-injured lung affects TGF-β1 induction in the lun...
The effect of SFN in cell viability of TGF-β1-stimulated cells for 24, 48, and 72 h. In A549 cells, ...
Additional file 4: Fig. S4. RNAscope analysis of Krt5: expressing AEC2s and Axin2+ AEC2s. High-magni...
Additional file 4: Fig. S4. RNAscope analysis of Krt5: expressing AEC2s and Axin2+ AEC2s. High-magni...
Additional file 1: Fig. S1. CTGF enhance the growth of AEC2s in vitro. (A) High-magnification images...
Additional file 6: Data file S1. The results of protein mass spectrometry of lung tissue post LPS-in...
Introduction: Chronic obstructive pulmonary disease (COPD) has high morbidity and mortality, with no...
Additional file 3: Fig. S3. RNA-seq analysis of Krt5 expressing AEC2s and Krt5− AEC2s: Krt5 expressi...
Additional file 5: Table S1. Overall clinical characteristics of patients with ARD
Figure S2. TGF-β1 concentrations in BAL fluid after administration of bleomycin. TGF-β1 concentratio...
<p>(A) and (D) are lung micrographs of a p66Shc−/− mouse at 7 months after CS exposure. (B) and (D) ...
Connective tissue growth factor (CTGF) is a newly described 38-kDa peptide mitogen for fibroblasts a...
Alveolar type II (ATII) cell proliferation and differentiation are important mechanisms in repair fo...
Connective tissue growth factor (CTGF) is a newly described 38-kDa peptide mitogen for fibroblasts a...
Alveolar type II (ATII) cell proliferation and differentiation are important mechanisms in repair fo...
Blockade of IL-6 at early inflammatory stage of BLM-injured lung affects TGF-β1 induction in the lun...
The effect of SFN in cell viability of TGF-β1-stimulated cells for 24, 48, and 72 h. In A549 cells, ...
Additional file 4: Fig. S4. RNAscope analysis of Krt5: expressing AEC2s and Axin2+ AEC2s. High-magni...
Additional file 4: Fig. S4. RNAscope analysis of Krt5: expressing AEC2s and Axin2+ AEC2s. High-magni...
Additional file 1: Fig. S1. CTGF enhance the growth of AEC2s in vitro. (A) High-magnification images...
Additional file 6: Data file S1. The results of protein mass spectrometry of lung tissue post LPS-in...
Introduction: Chronic obstructive pulmonary disease (COPD) has high morbidity and mortality, with no...
Additional file 3: Fig. S3. RNA-seq analysis of Krt5 expressing AEC2s and Krt5− AEC2s: Krt5 expressi...
Additional file 5: Table S1. Overall clinical characteristics of patients with ARD
Figure S2. TGF-β1 concentrations in BAL fluid after administration of bleomycin. TGF-β1 concentratio...
<p>(A) and (D) are lung micrographs of a p66Shc−/− mouse at 7 months after CS exposure. (B) and (D) ...
Connective tissue growth factor (CTGF) is a newly described 38-kDa peptide mitogen for fibroblasts a...
Alveolar type II (ATII) cell proliferation and differentiation are important mechanisms in repair fo...
Connective tissue growth factor (CTGF) is a newly described 38-kDa peptide mitogen for fibroblasts a...
Alveolar type II (ATII) cell proliferation and differentiation are important mechanisms in repair fo...
Blockade of IL-6 at early inflammatory stage of BLM-injured lung affects TGF-β1 induction in the lun...
The effect of SFN in cell viability of TGF-β1-stimulated cells for 24, 48, and 72 h. In A549 cells, ...