Phenotypic screening is a type of screening used to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner. When the molecular mechanism of action is not assumed and does not require knowledge of the molecular target, phenotypic screening can be applied in biological research and drug discovery
Abstract With the development of advanced technologies in cell-based phenotypic screening, phenotypi...
Cell-permeable compounds provide a convenient and efficient approach to manipulate biological proces...
Stem-cell-derived tissue models generated from sick people are being used to understand human develo...
A phenocopy is defined as an environmentally induced phenotype of one individual which is identical ...
There has been a renewed interest in cell-based phenotypic screening in drug discovery with the goal...
High throughput drug screening has greatly progressed drug discovery for diseases such as cancer. Sp...
High throughput drug screening has greatly progressed drug discovery for diseases such as cancer. Sp...
Stem cells display a fundamentally different mechanism of proliferation control when compared to som...
Stem cells display a fundamentally different mechanism of proliferation control when compared to som...
International audienceWith the development of advanced technologies in cell-based phenotypic screeni...
In the genomic era of 1990s-2000s, pharmaceutical research moved to target-based drug discovery whic...
Recent drug discovery efforts have utilized high throughput screening (HTS) of large chemical librar...
Biologically active small molecules have a central role in drug development, and as chemical probes ...
International audienceCell-based phenotypic screening has proven to be valuable, notably in recapitu...
A phenocopy is defined as an environmentally induced phenotype of one individual which is identical ...
Abstract With the development of advanced technologies in cell-based phenotypic screening, phenotypi...
Cell-permeable compounds provide a convenient and efficient approach to manipulate biological proces...
Stem-cell-derived tissue models generated from sick people are being used to understand human develo...
A phenocopy is defined as an environmentally induced phenotype of one individual which is identical ...
There has been a renewed interest in cell-based phenotypic screening in drug discovery with the goal...
High throughput drug screening has greatly progressed drug discovery for diseases such as cancer. Sp...
High throughput drug screening has greatly progressed drug discovery for diseases such as cancer. Sp...
Stem cells display a fundamentally different mechanism of proliferation control when compared to som...
Stem cells display a fundamentally different mechanism of proliferation control when compared to som...
International audienceWith the development of advanced technologies in cell-based phenotypic screeni...
In the genomic era of 1990s-2000s, pharmaceutical research moved to target-based drug discovery whic...
Recent drug discovery efforts have utilized high throughput screening (HTS) of large chemical librar...
Biologically active small molecules have a central role in drug development, and as chemical probes ...
International audienceCell-based phenotypic screening has proven to be valuable, notably in recapitu...
A phenocopy is defined as an environmentally induced phenotype of one individual which is identical ...
Abstract With the development of advanced technologies in cell-based phenotypic screening, phenotypi...
Cell-permeable compounds provide a convenient and efficient approach to manipulate biological proces...
Stem-cell-derived tissue models generated from sick people are being used to understand human develo...
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