HVEM-/- mice were ocularly infected with 2X105 pfu/eye of KOS-Rid1, KOS-Rid2, or control KOS after corneal scarification. Twenty-eight days PI, individual TGs were isolated and incubated in tissue culture media as in Fig 1 above. Results are plotted as the number of TG that reactivated daily. Numbers indicate average time that TG from each group first showed CPE ± SEM. For each group 20 TG from ten mice were used.</p
<p>Sts dKO and C57BL/6 WT mice were infected with 1000 PFU of MHV68 by the intranasal route and sing...
<p>(A) Experimental scheme. Groups of BALB/c (index) mice were infected with 50 PFU ECTV-WT, rested ...
<p>C57BL/6 mice infected with HSV-1 were treated with various concentrations of FTY720 or vehicle 24...
<p>Corneas of B6 mice were infected with 1x10<sup>5</sup> PFU of WT or S1L HSV-1. At 34 dpi latently...
The present study reviews the development of an effective murine iontophoresis reactivation model fo...
The exact mechanisms of HSV-1 establishment, maintenance, latency, reactivation, and also the course...
PurposeBlinding ocular herpetic disease in humans is due to spontaneous reactivation of herpes simpl...
<div><p>The establishment of latent infections in sensory neurons is a remarkably effective immune e...
<p><b>(A)</b> Percentage of reactivating ipsilateral or contralateral trigeminal ganglia from HSV‑1 ...
<p>A) Infection of mice with virulent HSV-1 strain McKrae. BXH2 or wild-type (WT) C3H/HEJ mice were ...
AbstractA recombinant HSV-1 virus expressing EGFP from the HCMV major immediate early promoter (KOS-...
<p>C57BL/6 mice were infected at 1000 PFU by the intraperitoneal route with the indicated viruses. <...
<p>(<b>A</b>) Number of infected (β-galactosidase<sup>+</sup>) cells from KOS/pCMV/eGC infected DRG ...
<p>1-d-old Tg and non-Tg mice were injected s.c. with 1×10<sup>7</sup> pfu of E59 or N-2838, and 7-d...
<p>On Day 70, naïve or live-0ΔNLS-immunized mice were challenged with 200,000 pfu per eye of HSV-2 M...
<p>Sts dKO and C57BL/6 WT mice were infected with 1000 PFU of MHV68 by the intranasal route and sing...
<p>(A) Experimental scheme. Groups of BALB/c (index) mice were infected with 50 PFU ECTV-WT, rested ...
<p>C57BL/6 mice infected with HSV-1 were treated with various concentrations of FTY720 or vehicle 24...
<p>Corneas of B6 mice were infected with 1x10<sup>5</sup> PFU of WT or S1L HSV-1. At 34 dpi latently...
The present study reviews the development of an effective murine iontophoresis reactivation model fo...
The exact mechanisms of HSV-1 establishment, maintenance, latency, reactivation, and also the course...
PurposeBlinding ocular herpetic disease in humans is due to spontaneous reactivation of herpes simpl...
<div><p>The establishment of latent infections in sensory neurons is a remarkably effective immune e...
<p><b>(A)</b> Percentage of reactivating ipsilateral or contralateral trigeminal ganglia from HSV‑1 ...
<p>A) Infection of mice with virulent HSV-1 strain McKrae. BXH2 or wild-type (WT) C3H/HEJ mice were ...
AbstractA recombinant HSV-1 virus expressing EGFP from the HCMV major immediate early promoter (KOS-...
<p>C57BL/6 mice were infected at 1000 PFU by the intraperitoneal route with the indicated viruses. <...
<p>(<b>A</b>) Number of infected (β-galactosidase<sup>+</sup>) cells from KOS/pCMV/eGC infected DRG ...
<p>1-d-old Tg and non-Tg mice were injected s.c. with 1×10<sup>7</sup> pfu of E59 or N-2838, and 7-d...
<p>On Day 70, naïve or live-0ΔNLS-immunized mice were challenged with 200,000 pfu per eye of HSV-2 M...
<p>Sts dKO and C57BL/6 WT mice were infected with 1000 PFU of MHV68 by the intranasal route and sing...
<p>(A) Experimental scheme. Groups of BALB/c (index) mice were infected with 50 PFU ECTV-WT, rested ...
<p>C57BL/6 mice infected with HSV-1 were treated with various concentrations of FTY720 or vehicle 24...