Superimposition of the CD64 best-fit models with the crystal structure of the Fc-CD64 complex.

The best-fit ribbon model for 0.11 mg/ml CD64 was overlaid on top of the crystal structure of IgG1-Fc (green and red surfaces) in complex with CD64 (black cartoon) (PDB code 4X4M). The structures were aligned upon the D2 domain of CD64 and the two views were rotated about the vertical axis by 90°. The CH2 and CH3 represent the constant domains, and the—A or—B represent their chain identity in the crystal structure. The IgG1-Fc glycans found in the crystal structure are shown as yellow sticks. Note that the crystal CD64 structure corresponds to that of Fig 7C.