UGTs are present in streptophytes and have diversified into many clades in the vascular lineage Angiosperms.

Cladogram of Archaeplastida phylogeny showing UGT clade origins and losses during plant evolution. The origins and losses of Family 28 glycosyltransferases are also shown. Blue circles represent first appearances of a clade, black circles represent the absence of a clade in a particular lineage. Also shown are the relative distributions of UGTs into their respective clades for each species included in our analysis, where each distinct coloured block represents either a separate UGT clade or a group of clades.