Workflow of methods.

Workflow displays different processing steps and each methods duration in minutes (‘). Segmentation-based analysis by operator 1 (SBA 1) included four major segmentation steps, operator 2 (SBA 2) displayed three steps. Model-free analysis (MFA) did not include a segmentation and used the entire field of view as seeding area for deterministic fiber tracking. Within MFA the red cross symbolises the manual exclusion of tracts outside of the highlighted supraspinatus muscle (blue color).