Add to ORKGThe anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated the anticancer mechanisms of DS/Cuusingin vitrocytotoxicity and metabolic kinetic analysis. Our studyindicates that DS/Cu targets cancer cells by the combination oftwo types of actions: (1) instant killing executed by DS/Cu reactiongenerated reactive oxygen species; (2) delayed cytotoxicity intro-duced by the end product, DDC-Cu. Nanoencapsulation of DSmight shed light on repositioning of DS into cancer treatment
Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of al...
<div><p>Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibit...
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates the a...
Abstract Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer acti...
<p><b>(A)</b> Disulfiram is metabolized to diethyldithiocarbamate (DDC) and DDC complexes with Coppe...
The alcohol-abuse deterrent disulfiram (DSF) is shown to have a highly selective toxicity against me...
Background: Disulfiram (DS), an anti-alcoholism drug, demonstrates strong antitumor activity in a co...
BACKGROUND:Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have an...
�� 2018 The Author(s). Background: Disulfiram (DS), an antialcoholism medicine, demonstrated strong ...
Abstract Disulfiram has been used for several decades in the treatment of alcoholism. It now shows p...
Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of al...
<div><p>Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibit...
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates the a...
Abstract Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer acti...
<p><b>(A)</b> Disulfiram is metabolized to diethyldithiocarbamate (DDC) and DDC complexes with Coppe...
The alcohol-abuse deterrent disulfiram (DSF) is shown to have a highly selective toxicity against me...
Background: Disulfiram (DS), an anti-alcoholism drug, demonstrates strong antitumor activity in a co...
BACKGROUND:Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have an...
�� 2018 The Author(s). Background: Disulfiram (DS), an antialcoholism medicine, demonstrated strong ...
Abstract Disulfiram has been used for several decades in the treatment of alcoholism. It now shows p...
Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of al...
<div><p>Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibit...
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity...