Background: Current guidelines for the treatment of hypertension recommends the combination therapy which should control of blood pressure and enhance cardiovascular protection. Materials and Methods: A sensitive, reliable and selective tandem mass spectrometry (LC-MS/MS) method has been developed for simultaneous quantification of amlodipine (AML), valsartan (VAL) and hydrochlorothiazide (HCTZ) in human plasma. The chromatographic system was equipped with ACE 5 C8 (50 X 2.1 mm) column and utilized a mobile phase composition of 0.5 mM Ammonium Chloride & 0.04% FA-Methanol (45:55% v/v). The method used three internal standards; AML-D4,HCTZ-D2 C13 and VAL-D3 with 10% intra- and inter-day precision, 6% bias for all the analytes. Results: The ...
A simple and selective HPLC-DAD stability indicating method was developed for the simultaneous deter...
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihype...
AbstractSimple and selective HPTLC methods were developed for the simultaneous determination of the ...
Background: Current guidelines for the treatment of hypertension recommends the combination therapy ...
A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric (LC-MS/MS) method ha...
Polypill is a fixed-dose combination that contains three or more active ingredients used as a single...
AbstractPolypill is a fixed-dose combination that contains three or more active ingredients used as ...
Objective: The aim of the study was to evaluate the bioequivalence between a newly developed generic...
Accurate, sensitive and reproducible reversed-phase high-perform-ance liquid chromatography (RP-HPLC...
A simple, specific, accurate and precise, stability indicating HPLC method for the simultaneous dete...
Background: Therapy-refractory arterial hypertension is defined as a blood pressure (BP) in a subset...
AbstractPolypill is a fixed-dose combination that contains three or more active ingredients used as ...
Accurate, sensitive and reproducible reversed-phase high-perform-ance liquid chromatography (RP-HPLC...
Abstract Cardiovascular disorders are among the leading causes of death worldwide, especially hypert...
AbstractA simple and selective HPLC-DAD stability indicating method was developed for the simultaneo...
A simple and selective HPLC-DAD stability indicating method was developed for the simultaneous deter...
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihype...
AbstractSimple and selective HPTLC methods were developed for the simultaneous determination of the ...
Background: Current guidelines for the treatment of hypertension recommends the combination therapy ...
A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric (LC-MS/MS) method ha...
Polypill is a fixed-dose combination that contains three or more active ingredients used as a single...
AbstractPolypill is a fixed-dose combination that contains three or more active ingredients used as ...
Objective: The aim of the study was to evaluate the bioequivalence between a newly developed generic...
Accurate, sensitive and reproducible reversed-phase high-perform-ance liquid chromatography (RP-HPLC...
A simple, specific, accurate and precise, stability indicating HPLC method for the simultaneous dete...
Background: Therapy-refractory arterial hypertension is defined as a blood pressure (BP) in a subset...
AbstractPolypill is a fixed-dose combination that contains three or more active ingredients used as ...
Accurate, sensitive and reproducible reversed-phase high-perform-ance liquid chromatography (RP-HPLC...
Abstract Cardiovascular disorders are among the leading causes of death worldwide, especially hypert...
AbstractA simple and selective HPLC-DAD stability indicating method was developed for the simultaneo...
A simple and selective HPLC-DAD stability indicating method was developed for the simultaneous deter...
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihype...
AbstractSimple and selective HPTLC methods were developed for the simultaneous determination of the ...