Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatment of acute myeloid and acute lymphoid leukemia are disclosed. Small molecules interfere with the interaction of MLL with any of its binding partners
Chromosomal rearrangements of the mixed lineage leukemia (MLL/KMT2A) gene leading to oncogenic MLL-f...
Glioblastoma is the most common primary malignant brain tumor in adults. The current inability to ef...
Resistance to androgen deprivation therapies and increased androgen receptor (AR) activity are major...
Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatm...
Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatm...
SummaryChromosomal translocations affecting mixed lineage leukemia gene (MLL) result in acute leukem...
The protein–protein interaction (PPI) between menin and mixed lineage leukemia (MLL) plays a critica...
ABSTRACT: The protein−protein interaction (PPI) be-tween menin and mixed lineage leukemia (MLL) play...
The interaction between menin and oncogenic mixed lineage leukemia (MLL) fusion proteins is required...
Menin is an essential oncogenic cofactor for mixed lineage leukemia 1 (MLL1)-mediated leukemogenesis...
Chromosomal translocations affecting mixed lineage leukemia gene (MLL) result in acute leukemias res...
Introduction of the N,N-dimethylaminoethoxy group to pyrido[3,2-d]pyrimidine led to the discovery of...
The protein–protein interaction between menin and mixed-lineage leukemia 1 (MLL1) plays an important...
Several acute myeloid leukemia genetic sub-types converge on high expression of HOX genes, critical ...
Rearrangements of the mixed lineage leukemia gene MLL are associated with aggressive lymphoid and my...
Chromosomal rearrangements of the mixed lineage leukemia (MLL/KMT2A) gene leading to oncogenic MLL-f...
Glioblastoma is the most common primary malignant brain tumor in adults. The current inability to ef...
Resistance to androgen deprivation therapies and increased androgen receptor (AR) activity are major...
Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatm...
Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatm...
SummaryChromosomal translocations affecting mixed lineage leukemia gene (MLL) result in acute leukem...
The protein–protein interaction (PPI) between menin and mixed lineage leukemia (MLL) plays a critica...
ABSTRACT: The protein−protein interaction (PPI) be-tween menin and mixed lineage leukemia (MLL) play...
The interaction between menin and oncogenic mixed lineage leukemia (MLL) fusion proteins is required...
Menin is an essential oncogenic cofactor for mixed lineage leukemia 1 (MLL1)-mediated leukemogenesis...
Chromosomal translocations affecting mixed lineage leukemia gene (MLL) result in acute leukemias res...
Introduction of the N,N-dimethylaminoethoxy group to pyrido[3,2-d]pyrimidine led to the discovery of...
The protein–protein interaction between menin and mixed-lineage leukemia 1 (MLL1) plays an important...
Several acute myeloid leukemia genetic sub-types converge on high expression of HOX genes, critical ...
Rearrangements of the mixed lineage leukemia gene MLL are associated with aggressive lymphoid and my...
Chromosomal rearrangements of the mixed lineage leukemia (MLL/KMT2A) gene leading to oncogenic MLL-f...
Glioblastoma is the most common primary malignant brain tumor in adults. The current inability to ef...
Resistance to androgen deprivation therapies and increased androgen receptor (AR) activity are major...