Add to ORKGThe present invention relates to the preparation of amines from aldehydes and ketones by reductive amination with enzymes having a reductive aminase activity on aldehydes and ketones devoid of any carboxyl group gamma of the carbonyl group. The invention also relates to the enzymes per se and their uses in biocatalysis. The enzymes are derived from Mycobacterium smegmatis and vaccae, Cystobacter fuscus, Microbacterium sp. and Aminomonas paucivorans
The synthesis of structurally diverse amines is of fundamental significance in the pharmaceutical in...
The present invention relates to a novel enzymatically catalyzed method for the production of alipha...
Triple mutant K66Q/S149G/N262C (TM_pheDH) of Rhodococcus phenylalanine dehydrogenase (pheDH) was eng...
Amines constitute the major targets for the production of a plethora of chemical compounds that have...
International audienceThe biocatalytic asymmetric synthesis of amines from carbonyl compounds and am...
Abstract. Asymmetric reductive aminations are some of the most important reactions in the preparatio...
Löwe J, Ingram AA, Gröger H. Enantioselective synthesis of amines via reductive amination with a deh...
The use of enzymes, nature´s own catalysts, both isolated or as whole cells to perform chemical tran...
Reductive Aminases (RedAms) catalyze the asymmetric reductive amination of ketones with primary amin...
The asymmetric reductive amination of ketones enables the one-step synthesis of chiral amines from r...
Menzel A, Werner H, Altenbuchner J, Gröger H. From Enzymes to "Designer Bugs" in Reductive Amination...
Farnberger JE, Lorenz E, Richter N, Wendisch VF, Kroutil W. In vivo Plug-and-play: A Modular Multi-e...
International audienceNative amine dehydrogenases (nat-AmDHs) catalyze the ( S )-stereoselective red...
The asymmetric reductive amination of ketones represents an elegant and convenient way to obtain chi...
International audienceThe asymmetric reductive amination of ketones enables the one-step synthesis o...
The synthesis of structurally diverse amines is of fundamental significance in the pharmaceutical in...
The present invention relates to a novel enzymatically catalyzed method for the production of alipha...
Triple mutant K66Q/S149G/N262C (TM_pheDH) of Rhodococcus phenylalanine dehydrogenase (pheDH) was eng...
Amines constitute the major targets for the production of a plethora of chemical compounds that have...
International audienceThe biocatalytic asymmetric synthesis of amines from carbonyl compounds and am...
Abstract. Asymmetric reductive aminations are some of the most important reactions in the preparatio...
Löwe J, Ingram AA, Gröger H. Enantioselective synthesis of amines via reductive amination with a deh...
The use of enzymes, nature´s own catalysts, both isolated or as whole cells to perform chemical tran...
Reductive Aminases (RedAms) catalyze the asymmetric reductive amination of ketones with primary amin...
The asymmetric reductive amination of ketones enables the one-step synthesis of chiral amines from r...
Menzel A, Werner H, Altenbuchner J, Gröger H. From Enzymes to "Designer Bugs" in Reductive Amination...
Farnberger JE, Lorenz E, Richter N, Wendisch VF, Kroutil W. In vivo Plug-and-play: A Modular Multi-e...
International audienceNative amine dehydrogenases (nat-AmDHs) catalyze the ( S )-stereoselective red...
The asymmetric reductive amination of ketones represents an elegant and convenient way to obtain chi...
International audienceThe asymmetric reductive amination of ketones enables the one-step synthesis o...
The synthesis of structurally diverse amines is of fundamental significance in the pharmaceutical in...
The present invention relates to a novel enzymatically catalyzed method for the production of alipha...
Triple mutant K66Q/S149G/N262C (TM_pheDH) of Rhodococcus phenylalanine dehydrogenase (pheDH) was eng...