Full summary statistics for the publication "Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits". The files, bmi.UKBBsummary.txt and height.UKBBsummary.txt, contain tissue specific associations with body mass index (BMI) and height respectively. The suffix UKBB450k indicates results from all ~450,000 European ancestry individuals in UK Biobank. The suffix UKBB50k corresponds to results from a subset of 50,000 Europeans in the UK Biobank. The suffix PAGE corresponds to results from ~50,000 individuals in the Population Architecture using Genomics and Epidemiology (PAGE) study. The file PAGE_PrediXcan_associations.txt includes trait~tissue specifi...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
We tested whether DNA-methylation profiles account for inter-individual variation in body mass index...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
Background: Genetic understanding of complex traits has developed immensely over the past decade but...
Annotations of gene structures and regulatory elements can inform genome-wide association studies (G...
Previous genome-wide association studies (GWAS) of hematological traits have identified over 10 000 ...
Large-scale whole-genome sequence data sets offer novel opportunities to identify genetic variation ...
Genetic predisposition for complex traits often acts through multiple tissues at different time poin...
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cult...
This is a pre-copyedited, author-produced version of an article accepted for publication in [Human M...
We develop a Bayesian model (BayesRR-RC) that provides robust SNP-heritability estimation, an altern...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
We apply integrative approaches to expression quantitative loci (eQTLs) from 44 tissues from the Gen...
Approaches exploiting trait distribution extremes may be used to identify loci associated with commo...
Background: Gene-lifestyle interaction studies using GWAS data contribute to a better understanding ...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
We tested whether DNA-methylation profiles account for inter-individual variation in body mass index...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
Background: Genetic understanding of complex traits has developed immensely over the past decade but...
Annotations of gene structures and regulatory elements can inform genome-wide association studies (G...
Previous genome-wide association studies (GWAS) of hematological traits have identified over 10 000 ...
Large-scale whole-genome sequence data sets offer novel opportunities to identify genetic variation ...
Genetic predisposition for complex traits often acts through multiple tissues at different time poin...
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cult...
This is a pre-copyedited, author-produced version of an article accepted for publication in [Human M...
We develop a Bayesian model (BayesRR-RC) that provides robust SNP-heritability estimation, an altern...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
We apply integrative approaches to expression quantitative loci (eQTLs) from 44 tissues from the Gen...
Approaches exploiting trait distribution extremes may be used to identify loci associated with commo...
Background: Gene-lifestyle interaction studies using GWAS data contribute to a better understanding ...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...
We tested whether DNA-methylation profiles account for inter-individual variation in body mass index...
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic dis...