Images of normal and tumor-derived breast PDX (both H&E and IF)

Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.

Kiyuna, Tasuku
Murakami, Takashi
Tome, Yasunori
Igarashi, Kentaro
Kawaguchi, Kei
Russell, Tara
Eckardt, Mark A
Crompton, Joseph
Singh, Arun
Bernthal, Nicholas
Bukata, Susan
Federman, Noah
Kanaya, Fuminori
Eilber, Fritz C
Hoffman, Robert M

February 2017

Our laboratory pioneered patient-derived orthotopic xenograft (PDOX) mouse models using surgical ort...

Pathological section of five tumor tissues with hematoxylin and eosin staining.

Xing Yue Peng (14159912)
Bocun Dong (14159915)
Xiaohui Liu (6412)

November 2022

Images are downloaded from the TCGA database (https://portal.gdc.cancer.gov/). IDs are taken from th...

Patient-derived xenograft (PDX) models in basic and translational breast cancer research

Dobrolecki, L. E.
Airhart, S. D.
Alferez, D. G.
Aparicio, S.
Behbod, F.
Bentires-Alj, M.
Brisken, C.
Bult, C. J.
Cai, S.
Clarke, R. B.
Dowst, H.
Ellis, M. J.
Gonzalez-Suarez, E.
Iggo, R. D.
Kabos, P.
Li, S.
Lindeman, G. J.
Marangoni, E.
McCoy, A.
Meric-Bernstam, F.
Piwnica-Worms, H.
Poupon, M. F.
Reis-Filho, J.
Sartorius, C. A.
Scabia, V.
Sflomos, G.
Tu, Y.
Vaillant, F.
Visvader, J. E.
Welm, A.
Wicha, M. S.
Lewis, M. T.

January 2016

Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...

Additional file 1: of Heterogeneous expression of EPCAM in human circulating tumour cells from patient-derived xenografts

Chiara Agnoletto (674961)
Linda Minotti (4928155)
Laura Brulle-Soumare (5913470)
Lorenzo Pasquali (336053)
Marco Galasso (386419)
Fabio CorrĂ (4928170)
Federica Baldassari (4928164)
Jean-Gabriel Judde (3562988)
Stefano Cairo (3563012)
Stefano Volinia (19385)

October 2018

Table S1. Description of human tumours grafted to generate PDX models, and their main clinical featu...

Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse.

Du Manoir, Stanislas
Orsetti, Béatrice
Bras-Gonçalves, Rui
Nguyen, Tien-Tuan
Lasorsa, Laurence
Boissière, Florence
Massemin, Blandine
Colombo, Pierre-Emmanuel
Bibeau, Frédéric
Jacot, William
Theillet, Charles

February 2014

The authors wish to thank the personnel of the IRCM animal facility team, the histology (RHEM) platf...

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

Meehan, Terrence F
Conte, Nathalie
Goldstein, Theodore
Inghirami, Giorgio
Murakami, Mark A
Brabetz, Sebastian
Gu, Zhiping
Wiser, Jeffrey A
Dunn, Patrick
Begley, Dale A
Krupke, Debra M
Bertotti, Andrea
Bruna, Alejandra
Brush, Matthew H
Byrne, Annette T
Caldas, Carlos
Christie, Amanda L
Clark, Dominic A
Dowst, Heidi
Dry, Jonathan R
Doroshow, James H
Duchamp, Olivier
Evrard, Yvonne A
Ferretti, Stephane
Frese, Kristopher K
Goodwin, Neal C
Greenawalt, Danielle
Haendel, Melissa A
Hermans, Els
Houghton, Peter J
Jonkers, Jos
Kemper, Kristel
Khor, Tin O
Lewis, Michael T
Lloyd, K C Kent
Mason, Jeremy
Medico, Enzo
Neuhauser, Steven B
Olson, James M
Peeper, Daniel S
Rueda, Oscar M
Seong, Je Kyung
Trusolino, Livio
Vinolo, Emilie
Wechsler-Reya, Robert J
Weinstock, David M
Welm, Alana
Weroha, S John
Amant, Frédéric
Pfister, Stefan M
Kool, Marcel
Parkinson, Helen
Butte, Atul J
Bult, Carol J

November 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Meehan, Terrence F.
Conte, Nathalie
Goldstein, Theodore
Inghirami, Giorgio
Murakami, Mark A.
Brabetz, Sebastian
Gu, Zhiping
Wiser, Jeffrey A.
Dunn, Patrick
Begley, Dale A.
Krupke, Debra M.
Bertotti, Andrea
Bruna, Alejandra
Brush, Matthew H.
Byrne, Annette T.
Caldas, Carlos
Christie, Amanda L.
Clark, Dominic A.
Dowst, Heidi
Dry, Jonathan R.
Doroshow, James H.
Duchamp, Olivier
Evrard, Yvonne A.
Ferretti, Stephane
Frese, Kristopher K.
Goodwin, Neal C.
Greenawalt, Danielle
Haendel, Melissa A.
Hermans, Els
Houghton, Peter J.
Jonkers, Jos
Kemper, Kristel
Khor, Tin O.
Lewis, Michael T.
Lloyd, K. C. Kent
Mason, Jeremy
Medico, Enzo
Neuhauser, Steven B.
Olson, James M.
Peeper, Daniel S.
Rueda, Oscar M.
Seong, Je Kyung
Trusolino, Livio
Vinolo, Emilie
Wechsler-Reya, Robert J.
Weinstock, David M.
Welm, Alana
Weroha, S. John
Amant, Frédéric
Pfister, Stefan M.
Kool, Marcel
Parkinson, Helen
Butte, Atul J.
Bult, Carol J.

January 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, A
Rueda, OM
Greenwood, W
Batra, AS
Callari, M
Batra, RN
Pogrebniak, K
Sandoval, J
Cassidy, JW
Tufegdzic-Vidakovic, A
Sammut, S-J
Jones, L
Provenzano, E
Baird, R
Eirew, P
Hadfield, J
Eldridge, M
McLaren-Douglas, A
Barthorpe, A
Lightfoot, H
O'Connor, MJ
Gray, J
Cortes, J
Baselga, J
Marangoni, E
Welm, AL
Aparicio, S
Serra, V
Garnett, MJ
Caldas, C

September 2016

The inter- and intra-tumor heterogeneity of breast cancer needs to be adequately captured in pre-cli...

DRS and IFS of breast cancer and normal breast tissue.

Niyom Lue (118224)
Jeon Woong Kang (330975)
Chung-Chieh Yu (333933)
Ishan Barman (330976)
Narahara Chari Dingari (330973)
Michael S. Feld (333934)
Ramachandra R. Dasari (118230)
Maryann Fitzmaurice (333936)

February 2013

<p>Diagram of normal and breast cancer tissues placed on glass plate during scanning (A); Gross phot...

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Bruna, Alejandra
Rueda, Oscar M.
Greenwood, Wendy
Batra, Ankita Sati
Callari, Maurizio
Batra, Rajbir Nath
Pogrebniak, Katherine
Sandoval, Jose
Cassidy, John W.
Tufegdzic-Vidakovic, Ana
Sammut, Stephen-John
Jones, Linda
Provenzano, Elena
Baird, Richard
Eirew, Peter
Hadfield, James
Eldridge, Matthew
McLaren-Douglas, Anne
Barthorpe, Andrew
Lightfoot, Howard
O’Connor, Mark J.
Gray, Joe
Cortes, Javier
Baselga, Jose
Marangoni, Elisabetta
Welm, Alana L.
Aparicio, Samuel
Serra, Violeta
Garnett, Mathew J.
Caldas, Carlos

September 2016

SummaryThe inter- and intra-tumor heterogeneity of breast cancer needs to be adequately captured in ...

PDX-MI: Minimal information for patient-derived tumor xenograft models

Ferretti, Stephane Raymond

November 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient‐Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice

Kiyuna, Tasuku
Murakami, Takashi
Tome, Yasunori
Kawaguchi, Kei
Igarashi, Kentaro
Miyake, Kentaro
Kanaya, Fuminori
Singh, Arun
Eilber, Fritz C
Hoffman, Robert M

October 2017

A patient-derived orthotopic xenograft (PDOX) model of undifferentiated pleomorphic sarcoma (UPS) wa...

Patient-derived xenografts from cervical dysplasia and normal cervical tissue.

Luke I. Larmour (5900774)
Fiona L. Cousins (513090)
Julie A. Teague (5900777)
James A. Deane (740892)
Tom W. Jobling (5900780)
Caroline E. Gargett (118663)

October 2018

A) Two representative examples of the cystic structures formed from cervical dysplasia xenografts. H...

Hematoxylin and Eosin staining of PH003.

Gretchen Glaser (736824)
S. John Weroha (736825)
Marc A. Becker (736826)
Xiaonan Hou (736827)
Sergio Enderica-Gonzalez (736828)
Sean C. Harrington (736829)
Paul Haluska (736830)

May 2015

<p>Patient (A & B) and tumorgraft (C & D) tissues are shown. Images were captured with a 40x objecti...

Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma

Hayden, Annette
Manousopoulou, Antigoni
Cowie, Andrew
Walker, Robert C.
Sharpe, Benjamin P.
Harrington, Jack
Izadi, Fereshteh
Breininger, Stella P.
Kyle, Ewan
Saunders, John H.
Parsons, Simon L.
Collier, Pamela
Ritchie, Alison A.
Clarke, Philip A.
Garbis, Spiros D.
Rose-Zerilli, Matthew
Grabowska, Anna M.
Underwood, Timothy J.

August 2021

These are whole-slide digital pathology images of esophageal adenocarcinoma (EAC) patient-derived xe...

Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.

Kiyuna, Tasuku
Murakami, Takashi
Tome, Yasunori
Igarashi, Kentaro
Kawaguchi, Kei
Russell, Tara
Eckardt, Mark A
Crompton, Joseph
Singh, Arun
Bernthal, Nicholas
Bukata, Susan
Federman, Noah
Kanaya, Fuminori
Eilber, Fritz C
Hoffman, Robert M

February 2017

Our laboratory pioneered patient-derived orthotopic xenograft (PDOX) mouse models using surgical ort...

Pathological section of five tumor tissues with hematoxylin and eosin staining.

Xing Yue Peng (14159912)
Bocun Dong (14159915)
Xiaohui Liu (6412)

November 2022

Images are downloaded from the TCGA database (https://portal.gdc.cancer.gov/). IDs are taken from th...

Patient-derived xenograft (PDX) models in basic and translational breast cancer research

Dobrolecki, L. E.
Airhart, S. D.
Alferez, D. G.
Aparicio, S.
Behbod, F.
Bentires-Alj, M.
Brisken, C.
Bult, C. J.
Cai, S.
Clarke, R. B.
Dowst, H.
Ellis, M. J.
Gonzalez-Suarez, E.
Iggo, R. D.
Kabos, P.
Li, S.
Lindeman, G. J.
Marangoni, E.
McCoy, A.
Meric-Bernstam, F.
Piwnica-Worms, H.
Poupon, M. F.
Reis-Filho, J.
Sartorius, C. A.
Scabia, V.
Sflomos, G.
Tu, Y.
Vaillant, F.
Visvader, J. E.
Welm, A.
Wicha, M. S.
Lewis, M. T.

January 2016

Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...

Additional file 1: of Heterogeneous expression of EPCAM in human circulating tumour cells from patient-derived xenografts

Chiara Agnoletto (674961)
Linda Minotti (4928155)
Laura Brulle-Soumare (5913470)
Lorenzo Pasquali (336053)
Marco Galasso (386419)
Fabio CorrĂ (4928170)
Federica Baldassari (4928164)
Jean-Gabriel Judde (3562988)
Stefano Cairo (3563012)
Stefano Volinia (19385)

October 2018

Table S1. Description of human tumours grafted to generate PDX models, and their main clinical featu...

Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse.

Du Manoir, Stanislas
Orsetti, Béatrice
Bras-Gonçalves, Rui
Nguyen, Tien-Tuan
Lasorsa, Laurence
Boissière, Florence
Massemin, Blandine
Colombo, Pierre-Emmanuel
Bibeau, Frédéric
Jacot, William
Theillet, Charles

February 2014

The authors wish to thank the personnel of the IRCM animal facility team, the histology (RHEM) platf...

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

Meehan, Terrence F
Conte, Nathalie
Goldstein, Theodore
Inghirami, Giorgio
Murakami, Mark A
Brabetz, Sebastian
Gu, Zhiping
Wiser, Jeffrey A
Dunn, Patrick
Begley, Dale A
Krupke, Debra M
Bertotti, Andrea
Bruna, Alejandra
Brush, Matthew H
Byrne, Annette T
Caldas, Carlos
Christie, Amanda L
Clark, Dominic A
Dowst, Heidi
Dry, Jonathan R
Doroshow, James H
Duchamp, Olivier
Evrard, Yvonne A
Ferretti, Stephane
Frese, Kristopher K
Goodwin, Neal C
Greenawalt, Danielle
Haendel, Melissa A
Hermans, Els
Houghton, Peter J
Jonkers, Jos
Kemper, Kristel
Khor, Tin O
Lewis, Michael T
Lloyd, K C Kent
Mason, Jeremy
Medico, Enzo
Neuhauser, Steven B
Olson, James M
Peeper, Daniel S
Rueda, Oscar M
Seong, Je Kyung
Trusolino, Livio
Vinolo, Emilie
Wechsler-Reya, Robert J
Weinstock, David M
Welm, Alana
Weroha, S John
Amant, Frédéric
Pfister, Stefan M
Kool, Marcel
Parkinson, Helen
Butte, Atul J
Bult, Carol J

November 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Meehan, Terrence F.
Conte, Nathalie
Goldstein, Theodore
Inghirami, Giorgio
Murakami, Mark A.
Brabetz, Sebastian
Gu, Zhiping
Wiser, Jeffrey A.
Dunn, Patrick
Begley, Dale A.
Krupke, Debra M.
Bertotti, Andrea
Bruna, Alejandra
Brush, Matthew H.
Byrne, Annette T.
Caldas, Carlos
Christie, Amanda L.
Clark, Dominic A.
Dowst, Heidi
Dry, Jonathan R.
Doroshow, James H.
Duchamp, Olivier
Evrard, Yvonne A.
Ferretti, Stephane
Frese, Kristopher K.
Goodwin, Neal C.
Greenawalt, Danielle
Haendel, Melissa A.
Hermans, Els
Houghton, Peter J.
Jonkers, Jos
Kemper, Kristel
Khor, Tin O.
Lewis, Michael T.
Lloyd, K. C. Kent
Mason, Jeremy
Medico, Enzo
Neuhauser, Steven B.
Olson, James M.
Peeper, Daniel S.
Rueda, Oscar M.
Seong, Je Kyung
Trusolino, Livio
Vinolo, Emilie
Wechsler-Reya, Robert J.
Weinstock, David M.
Welm, Alana
Weroha, S. John
Amant, Frédéric
Pfister, Stefan M.
Kool, Marcel
Parkinson, Helen
Butte, Atul J.
Bult, Carol J.

January 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, A
Rueda, OM
Greenwood, W
Batra, AS
Callari, M
Batra, RN
Pogrebniak, K
Sandoval, J
Cassidy, JW
Tufegdzic-Vidakovic, A
Sammut, S-J
Jones, L
Provenzano, E
Baird, R
Eirew, P
Hadfield, J
Eldridge, M
McLaren-Douglas, A
Barthorpe, A
Lightfoot, H
O'Connor, MJ
Gray, J
Cortes, J
Baselga, J
Marangoni, E
Welm, AL
Aparicio, S
Serra, V
Garnett, MJ
Caldas, C

September 2016

The inter- and intra-tumor heterogeneity of breast cancer needs to be adequately captured in pre-cli...

DRS and IFS of breast cancer and normal breast tissue.

Niyom Lue (118224)
Jeon Woong Kang (330975)
Chung-Chieh Yu (333933)
Ishan Barman (330976)
Narahara Chari Dingari (330973)
Michael S. Feld (333934)
Ramachandra R. Dasari (118230)
Maryann Fitzmaurice (333936)

February 2013

<p>Diagram of normal and breast cancer tissues placed on glass plate during scanning (A); Gross phot...

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Bruna, Alejandra
Rueda, Oscar M.
Greenwood, Wendy
Batra, Ankita Sati
Callari, Maurizio
Batra, Rajbir Nath
Pogrebniak, Katherine
Sandoval, Jose
Cassidy, John W.
Tufegdzic-Vidakovic, Ana
Sammut, Stephen-John
Jones, Linda
Provenzano, Elena
Baird, Richard
Eirew, Peter
Hadfield, James
Eldridge, Matthew
McLaren-Douglas, Anne
Barthorpe, Andrew
Lightfoot, Howard
O’Connor, Mark J.
Gray, Joe
Cortes, Javier
Baselga, Jose
Marangoni, Elisabetta
Welm, Alana L.
Aparicio, Samuel
Serra, Violeta
Garnett, Mathew J.
Caldas, Carlos

September 2016

SummaryThe inter- and intra-tumor heterogeneity of breast cancer needs to be adequately captured in ...

PDX-MI: Minimal information for patient-derived tumor xenograft models

Ferretti, Stephane Raymond

November 2017

Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research pl...

Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient‐Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice

Kiyuna, Tasuku
Murakami, Takashi
Tome, Yasunori
Kawaguchi, Kei
Igarashi, Kentaro
Miyake, Kentaro
Kanaya, Fuminori
Singh, Arun
Eilber, Fritz C
Hoffman, Robert M

October 2017

A patient-derived orthotopic xenograft (PDOX) model of undifferentiated pleomorphic sarcoma (UPS) wa...

Patient-derived xenografts from cervical dysplasia and normal cervical tissue.

Luke I. Larmour (5900774)
Fiona L. Cousins (513090)
Julie A. Teague (5900777)
James A. Deane (740892)
Tom W. Jobling (5900780)
Caroline E. Gargett (118663)

October 2018

A) Two representative examples of the cystic structures formed from cervical dysplasia xenografts. H...

Hematoxylin and Eosin staining of PH003.

Gretchen Glaser (736824)
S. John Weroha (736825)
Marc A. Becker (736826)
Xiaonan Hou (736827)
Sergio Enderica-Gonzalez (736828)
Sean C. Harrington (736829)
Paul Haluska (736830)

May 2015

<p>Patient (A & B) and tumorgraft (C & D) tissues are shown. Images were captured with a 40x objecti...

Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma

Hayden, Annette
Manousopoulou, Antigoni
Cowie, Andrew
Walker, Robert C.
Sharpe, Benjamin P.
Harrington, Jack
Izadi, Fereshteh
Breininger, Stella P.
Kyle, Ewan
Saunders, John H.
Parsons, Simon L.
Collier, Pamela
Ritchie, Alison A.
Clarke, Philip A.
Garbis, Spiros D.
Rose-Zerilli, Matthew
Grabowska, Anna M.
Underwood, Timothy J.

August 2021

These are whole-slide digital pathology images of esophageal adenocarcinoma (EAC) patient-derived xe...

Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.

Kiyuna, Tasuku
Murakami, Takashi
Tome, Yasunori
Igarashi, Kentaro
Kawaguchi, Kei
Russell, Tara
Eckardt, Mark A
Crompton, Joseph
Singh, Arun
Bernthal, Nicholas
Bukata, Susan
Federman, Noah
Kanaya, Fuminori
Eilber, Fritz C
Hoffman, Robert M

February 2017

Our laboratory pioneered patient-derived orthotopic xenograft (PDOX) mouse models using surgical ort...

Pathological section of five tumor tissues with hematoxylin and eosin staining.

Xing Yue Peng (14159912)
Bocun Dong (14159915)
Xiaohui Liu (6412)

November 2022

Images are downloaded from the TCGA database (https://portal.gdc.cancer.gov/). IDs are taken from th...

Patient-derived xenograft (PDX) models in basic and translational breast cancer research

Dobrolecki, L. E.
Airhart, S. D.
Alferez, D. G.
Aparicio, S.
Behbod, F.
Bentires-Alj, M.
Brisken, C.
Bult, C. J.
Cai, S.
Clarke, R. B.
Dowst, H.
Ellis, M. J.
Gonzalez-Suarez, E.
Iggo, R. D.
Kabos, P.
Li, S.
Lindeman, G. J.
Marangoni, E.
McCoy, A.
Meric-Bernstam, F.
Piwnica-Worms, H.
Poupon, M. F.
Reis-Filho, J.
Sartorius, C. A.
Scabia, V.
Sflomos, G.
Tu, Y.
Vaillant, F.
Visvader, J. E.
Welm, A.
Wicha, M. S.
Lewis, M. T.

January 2016

Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...

Images of normal and tumor-derived breast PDX (both H&E and IF)

Abstract

Extracted data

Images of normal and tumor-derived breast PDX (both H&E and IF)

Abstract

Extracted data

Topics

Related items

Topics

Related items