This is the consensus sequence repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models". It contains the 10% consensus nucleotide sequences of the env and gag (only p24) protein of HIV-1 used for the training and leftout data set. The NGS sequences are available under BioProject ID PRJNA810303 and the corresponding BioSample Accession IDs are SAMN26241863:26242168 and SAMN28728524:SAMN28728529 env_leftout.fasta A fasta file that contains the consensus nucleotide sequences for the env protein for the leftout data set env_nt_274.fasta A fasta file that contains the consensus nucleotide sequences for the env protein for the training data set ...
\sectionMotivation:} Due to the high mutation rate of HIV, drug resistant variants emerge frequently...
The broadly neutralizing antibody (bnAb) VRC01 is being evaluated for its efficacy to prevent HIV-1 ...
<div><p>The ability to determine coreceptor usage of patient-derived human immunodeficiency virus ty...
This is the data repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA ...
Single-molecule long-read sequencing technology recently reached accuracies useful for studying dive...
Acquired Immunodeficiency Syndrome (AIDS) caused by Human Immunodeficiency Virus is a serious public...
<p>A) Distribution of known mutant origins across viral ARF sequences attributable to a particular c...
Early in infection, human immunodeficiency virus type 1 (HIV-1) generally uses the CCR5 chemokine re...
<p>At each position in cEnv (Env 521–606) where consensus amino acids differ between clades, the fre...
<p>At each position in cGag-1 (Gag 148–214) where consensus amino acids differ between clades, the f...
<p>CRF sequences were grouped in 12 recombinant families; no, number; CRF, circulating recombinant f...
<p>At each position in cGag-2 (Gag 250–335) where consensus amino acids differ between clades, the f...
The high level of genetic diversity of HIV-1 poses a major challenge for global vaccine development....
<p>(A) A valine (V) at amino acid position 303 of HIV-1 Gag was significantly (<i>p <</i> 0.001, Fis...
<p>The experimentally identified positions are defined as those at which alanine point mutations wer...
\sectionMotivation:} Due to the high mutation rate of HIV, drug resistant variants emerge frequently...
The broadly neutralizing antibody (bnAb) VRC01 is being evaluated for its efficacy to prevent HIV-1 ...
<div><p>The ability to determine coreceptor usage of patient-derived human immunodeficiency virus ty...
This is the data repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA ...
Single-molecule long-read sequencing technology recently reached accuracies useful for studying dive...
Acquired Immunodeficiency Syndrome (AIDS) caused by Human Immunodeficiency Virus is a serious public...
<p>A) Distribution of known mutant origins across viral ARF sequences attributable to a particular c...
Early in infection, human immunodeficiency virus type 1 (HIV-1) generally uses the CCR5 chemokine re...
<p>At each position in cEnv (Env 521–606) where consensus amino acids differ between clades, the fre...
<p>At each position in cGag-1 (Gag 148–214) where consensus amino acids differ between clades, the f...
<p>CRF sequences were grouped in 12 recombinant families; no, number; CRF, circulating recombinant f...
<p>At each position in cGag-2 (Gag 250–335) where consensus amino acids differ between clades, the f...
The high level of genetic diversity of HIV-1 poses a major challenge for global vaccine development....
<p>(A) A valine (V) at amino acid position 303 of HIV-1 Gag was significantly (<i>p <</i> 0.001, Fis...
<p>The experimentally identified positions are defined as those at which alanine point mutations wer...
\sectionMotivation:} Due to the high mutation rate of HIV, drug resistant variants emerge frequently...
The broadly neutralizing antibody (bnAb) VRC01 is being evaluated for its efficacy to prevent HIV-1 ...
<div><p>The ability to determine coreceptor usage of patient-derived human immunodeficiency virus ty...