Here we provide a complete workflow for the preprocessing and analysis of DNA methylation array data. The workflow combines best practices in the field with in-house developed methodology, and is geared towards large-scale studies, including Epigenome-wide Association Studies (EWAS). Its development was informed by our research analysing BIOS consortium data, which contains multiomics measures from 6 Dutch biobanks comprising ~4000 individuals
Summary: The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA methy...
Epigenetics is the study of heritable changes in gene function that occur without a change in DNA se...
2013-07-23In the first chapter of this dissertation, I review the importance of cytosine methylation...
Here we provide a complete workflow for the preprocessing and analysis of DNA methylation array data...
<p>Here, https://git.lumc.nl/molepi/Leiden450K, we provide a complete workflow for the the preproces...
The promise of epigenome-wide association studies and cancer-specific somatic DNA methylation change...
Methylation in the human genome is known to be associated with development and disease. The Illumina...
Methylation in the human genome is known to be associated with development and disease. The Illumina...
Abstract Background DNA methylation has been identified to be widely associated to complex diseases....
Background: As the most stable and experimentally accessible epigenetic mark, DNA methylation is of ...
Abstract Objective Illumina BeadChip arrays are commonly used to generate DNA methylation data for l...
ABSTRACT Summary: The Illumina 450k array is a frequently used platform for largescale genome-wide D...
The promise of epigenome-wide association studies and cancer-specific somatic DNA methylation change...
DNA Methylation (DNAm) is an epigenetic modification that is present across the human genome, primar...
Summary:The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA methyl...
Summary: The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA methy...
Epigenetics is the study of heritable changes in gene function that occur without a change in DNA se...
2013-07-23In the first chapter of this dissertation, I review the importance of cytosine methylation...
Here we provide a complete workflow for the preprocessing and analysis of DNA methylation array data...
<p>Here, https://git.lumc.nl/molepi/Leiden450K, we provide a complete workflow for the the preproces...
The promise of epigenome-wide association studies and cancer-specific somatic DNA methylation change...
Methylation in the human genome is known to be associated with development and disease. The Illumina...
Methylation in the human genome is known to be associated with development and disease. The Illumina...
Abstract Background DNA methylation has been identified to be widely associated to complex diseases....
Background: As the most stable and experimentally accessible epigenetic mark, DNA methylation is of ...
Abstract Objective Illumina BeadChip arrays are commonly used to generate DNA methylation data for l...
ABSTRACT Summary: The Illumina 450k array is a frequently used platform for largescale genome-wide D...
The promise of epigenome-wide association studies and cancer-specific somatic DNA methylation change...
DNA Methylation (DNAm) is an epigenetic modification that is present across the human genome, primar...
Summary:The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA methyl...
Summary: The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA methy...
Epigenetics is the study of heritable changes in gene function that occur without a change in DNA se...
2013-07-23In the first chapter of this dissertation, I review the importance of cytosine methylation...