Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies
- Greco, Beatrice
- Malacarne, Valeria
- Scotti, Giulia Maria
- Manfredi, Francesco
- Angelino, Elia
- Sirini, Camilla
- Camisa, Barbara
- Falcone, Laura
- Moresco, Marta Angiola
- Paolella, Katia
- Di Bono, Mattia
- Norata, Rossana
- Sanvito, Francesca
- Arcangeli, Silvia
- Doglioni, Claudio
- Ciceri, Fabio
- Bonini, Chiara
- Graziani, Andrea
- Bondanza, Attilio
- Casucci, Monica
Publication date
January 2022
DOIAbstract
Science Translational Medicine research article reporting that reducing the expression of N-glycans on tumor cells enhances the therapeutic potential of chimeric antigen receptor T cells against solid tumorsAccepted version before final editing. Find the final version at https://www.science.org/doi/10.1126/scitranslmed.abg307
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