Cognitive impairment restoration in patients suffered with stroke during the post-COVID period

Stoyanov O. M., Son A. S., Vastyanov R. S., Turchin N. I., Gruzevsky O. A., Yermuraki P. P., Dzygal O. F., Vastyanov M. R. Cognitive impairment restoration in patients suffered with stroke during the post-COVID period. Journal of Education, Health and Sport. 2022;12(2): 336-343. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.02.034 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.02.034 https://zenodo.org/record/6895998 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 1, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 1 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access ar6ticle licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 31.01.2022. Revised: 08.02.2022. Accepted: 28.02.2022. COGNITIVE IMPAIRMENT RESTORATION IN PATIENTS SUFFERED WITH STROKE DURING THE POST-COVID PERIOD O. M. Stoyanov, A. S. Son, R. S. Vastyanov, N. I. Turchin, O. A. Gruzevsky, P. P. Yermuraki, O. F. Dzygal, M. R. Vastyanov The Odessa National Medical University, Ukraine Abstract Frequency of vascular complications, including strokes, in patients suffered from COVID-19 infection is known to be increased up to 8 times, especially compared with influenza. The purpose: to investigate the fundamental mechanisms of brain ischemia in the patients with mnestic dysfunctions who previously underwent COVID-19 through pharmacocorrection via Phenibut (g-amino-b-phenylbutyric acid hydrochloride) and magnetic therapy in the early recovery period of ischemic stroke. The authors describe the possibilities of cognitive rehabilitation for people who have had ischemic stroke in the post-COVID period. Considering that the presence of mnestic dysfunctions has a negative impact on the process of rehabilitation of cerebral accidents, the fundamental mechanisms of brain ischemia in patients with mnestic dysfunctions in the early recovery period in patients who have undergone COVID-19 have been studied through pharmacocorrection via Phenibut (g-amino-b-phenylbutyric acid hydrochloride) and magnetic therapy. 46 patients aged 40 to 60 years were examined. A comparative study of three randomized clinical groups of patients with separate and complex use of Phenibut and magnetic stimulation. The effectiveness of the proposed therapy in restoring executive functions was established on the basis of indicators of the MMSE scale, the test for the study of frontal dysfunction – FAB, regression of depressive symptoms and is characterized by a decrease in the score on the GDS scale. The authors conclude that mnestic disorders are a functional "target" in cerebral ischemia in the post-COVID period, which requires close attention in relation to pharmacocorrection methods and comprehensive rehabilitation and further research, including the elucidate the pathogenetic mechanisms of cerebral ischemia. Key words: stroke; mnestic dysfunctions; pathogenetic mechanisms of cerebral ischemia; post-COVID period; pharmacological correction; magnetic therap