Polycystic Ovary Syndrome - increased risk of depression development

SZYMAŃSKA, Julia, KAPŁON, Kamil, PAWŁOCIK, Weronika, WOJTALA, Laura, PAWLAK, Weronika, KOJDER, Dominika, KAMIŃSKA, Izabela, GRABOWSKA, Ewa, MUSIAŁ, Lena & MOŻDŻYŃSKA, Agnieszka. Polycystic Ovary Syndrome - increased risk of depression development. Links and risk factors. Journal of Education, Health and Sport. 2023;17(1):21-26. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.17.01.002 https://apcz.umk.pl/JEHS/article/view/42948 https://zenodo.org/record/7769382 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2023; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 06.03.2023. Revised: 14.03.2023. Accepted: 24.03.2023. Published: 25.03.2023. Polycystic Ovary Syndrome - increased risk of depression development. Links and risk factors Julia Szymańska Szpital Miejski im. Franciszka Raszei ul. Mickiewicza 2, 60-834 Poznań https://orcid.org/0000-0001-6113-5046 E-mail: julmagszy@gmail.com Kamil Kapłon Uniwersytecki Szpital Kliniczny w Poznaniu ul. Przybyszewskiego 49, 60-355 Poznań https://orcid.org/0000-0002-8110-9352 E-mail: kamil.kaplon.2022@gmail.com Weronika Pawłocik Wojewódzki Szpital Zespolony w Lesznie, ul. Jana Kiepury 45, 64-115 Leszno https://orcid.org/0000-0001-7439-0820 E-mail: weronika.pawlocik96@gmail.com Laura Wojtala Uniwersytecki Szpital Kliniczny w Poznaniu, ul. Przybyszewskiego 49, 60-355 Poznań https://orcid.org/0000-0002-5715-2334 E-mail: lauramwojtala@gmail.com Weronika Pawlak Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych i Administracji w Poznaniu im. prof. Ludwika Bierkowskiego. ul. Dojazd 34, 60-631 Poznań https://orcid.org/0000-0002-6016-1119 E-mail: weronika.pawlak@interia.eu Dominika Kojder Samodzielny Publiczny Zakład Opieki Zdrowotnej w Przeworsku ul. Szpitalna 16 37-200 Przeworsk https://orcid.org/0000-0002-8915-4959, E-mail: dominika.kojder9@gmail.com Izabela Kamińska Szpital Czerniakowski sp. z o. o. , ul. Stępińska 19/25, 00-739 Warszawa https://orcid.org/0000-0002-5766-2262 E-mail: izakam303@gmail.com Ewa Grabowska Nowodworskie Centrum Medyczne ul. Miodowa 2, 05-100 Nowy Dwór Mazowiecki https://orcid.org/0000-0003-1426-5205 E-mail: ewamich343@gmail.com Lena Musiał Szpital Średzki Serca Jezusowego Sp. z o.o. ul. Żwirki i Wigury 10, 63-000 Środa Wielkopolska https://orcid.org/0000-0002-1998-6477 E-mail: musialka96@gmail.com Agnieszka Możdżyńska Szpital Średzki Serca Jezusowego Sp. z o.o. ul. Żwirki i Wigury 10, 63-000 Środa Wielkopolska https://orcid.org/0000-0001-8590-0486 E-mail: a.mozdzynska@icloud.com Abstract PCOS is a common endocrine disorder affecting up to 6-10% of women in reproductive age. Patients suffer from many manifestations of this disease including symptoms of hyperandrogenism (hirsutism, acne, androgenetic alopecia), ovulation disorders, infertility, overweight and obesity, glucose-insulin homeostasis disorders (insulin resistance, type 2 diabetes). Many studies emphasize the relationship between the presence of PCOS in patients and the appearance of depression. The median incidence of depression in women with this syndrome was 36.6%, while in the group of women without PCOS it was 14.2%. The exact mechanism of this relationship is still unknown, but many factors may play an important role in it, e.g. increased BMI, infertility, high cortisol levels, body image, vitamin D deficiency or elevated inflammation markers. Keywords: PCOS; depression; infertility; obesit