EVALUATION OF ROLE OF HYALURONIC ACID IN MANAGEMENT OF POST OPERATIVE SEQUALE OF MANDIBULAR THIRD MOLAR DISIMPACTION - A SPLIT-MOUTH COMPARATIVE STUDY

Aim of the study: To determine the efficacy of Hyaluronic acid gel in management of postoperative complications after impacted mandibular third molar surgery. Materials and Method : This prospective, single-centeredstudy follow a split mouth-design, where the patients were act as their own control. A total of 40 patients were included in study.The study subjects were assigned into two groups: Control Group and Study Group (0.8 % Hyaluronic acid gel). Once selected, each patient will be assigned a serial number. According to their respective serial numbers, patients with odd serial number will be administered 2ml 0.8% hyaluronic acid gel (Gengigel ) in the postextraction socket of impacted mandibular third molar of the left side, and the right side will act as control, an interval of 4 weeks is kept between the 2 surgeries. In even numbered patients, the right side extraction socket will be administered 2 ml 0.8 % hyaluronic acid gel (Gengigel)and the left side acted as the control. . Post-operative pain, trismus, swelling & soft tissue healing were evaluated on 1st, 3rd and 7th postoperative days . Results:0.8 % Hyaluronic acid gel has shown a beneficial results in the reduction of postoperative pain on 7th day and soft tissue healing on 3rd and 7th days , the results were statistically significant, although the results for trismus and swellingwas not statistically significant. Conclusion :The efficacy of Hyaluronic acid gel has proven to be an important therapeutic adjuvant for reducing postoperative pain & improve soft tissue healing following mandibular third molar surgery and thus improving patients quality of life