Effect of Chloroxylon swietenia Bark Extract On Lipid Profiles Of Diabetic Induced Wistar Rats

Abstract Diabetes mellitus is a metabolic disorder and not a disease, characterized by hyperglycemia resulting from defects in insulin secretion/synthesis/induction in to the cell and insulin action or both. This investigation was designed to study the anti lipidemic profiles was investigated in diabetic induced Wistar rats treated with plant extract. Diabetes was induced after a single dose of intraperitoneal injection of Alloxan monohydrate drug (120 mg/ kg). The parameters studied were lipidprofile like Total cholesterol (TC), Triglyceride (TG), High-density lipoprotein (HDL), Low-density lipoprotein (LDL).Theresult of test drug was compared with diabetic control. Glibenclamide (600µg/kg/bw) was selected as standard hypoglycaemic drug. 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