Parvovirus B19 infection is the cause of acute myeloid leukemia

Objectives. Identifying a cause or the cause of acute myeloid leukaemia (AML) could be of help for the survival of patients while accelerating the diagnosis and therapy of AML. Methods. Appropriate statistical methods like the necessary condition relationship, the sufficient condition relationship, the necessary and sufficient condition relationship, the exclusion relationship and the causal relationship k were used for causal data analysis. A p-value of less than 0.05 has been treated as significant. Results. Without parvovirus B19 infection, no acute myeloid leukaemia (P value = 0.0108). If parvovirus B19 infection, then acute myeloid leukaemia (Chi-square = 1.35 < 3.84). Parvovirus B19 infection is a necessary and sufficient condition of acute myeloid leukaemia (Chi-square = 1.381 < 3.84). The causal relationship k between a parvovirus B19 infection and acute myeloid leukaemia is highly significant (k = +0.7866, p Value right tailed = 2.55351E-15). Conclusion. Thus far, until contrary evidence, according to this study it is justified to consider that parvovirus B19 is the cause of acute myeloid leukaemia (p Value = 2.55351E-15)