ASSESSMENT FOR STORAGE OF LIQUID DOSAGE FORM AT HOME IN SOUTH JEDDAH CITY, KSA

Introduction: Liquid state forms are meant for internal and external use. They are available in monophonic and biphasic forms. Monophonic liquid dosage forms are true or colloidal solution. Water is mainly used as a solvent for a majority of monophasic liquid dosage forms. Hence, the present study was conducted to observe the storage of the oral liquid formulation during the usage. Methods: A retrospective observational study of 4 month duration was undertaken from Jan- April 2018. A total 100 number of participants have involved in the study. The data was interpreted and the results were articulated as counts and percentage. Results: Participants store the oral liquid formulation at room temperature i.e., 25-30°C (60.15%). The data also indicates that most of the parents will administer the medication 2-3 times per day. The percentage usage oral liquid formulations (internal use) and external liquid formulations are 79.1% and 9.8% respectively. However, the majority of the participants in the study used extemporaneously preparation are used for seven days (76.95%) and only 10.12% used for one month. The data also indicates that 62.56% of participants do not read the administration guideline or labels. Different tools for the administration of liquid dosage forms, the usage of syringe/ dropper are higher percentage (29.91%) whereas the usage of household spoon and medical cup is 24.05% and 24.01% respectively. As per the survey recorded it shows that the liquid formulation changes the color in higher percentage (32.5%) and then formation of the crystals i.e. (30.05%), it might be due to the storage of the formulation at room temperature. Conclusions: The results reflect a good level of correct practice. However, there is a room for improvement. The pharmacists are recommended to explain the correct directions for the storage and usage of the liquid oral formulations. Key Words: Liquid oral formulations. Retrospective observational study, Statistical analysi