ANALYSIS OF LIPID PROFILE IN DIABETIC PATIENTS AMONG LOCAL POPULATION OF PAKISTAN

Introduction: Diabetes mellitus is a metabolic disease characterized by the increase in blood glucose level as a result of insulin deficiency or insulin resistance. Aims and Objectives: The main objective of the study is to analyze the lipid profile in tpe-2 diabetic patients among local population of Pakistan. Methodology of the study: This cross sectional study was conducted in RHC, Rajanpur kalan, Rahim Yar Khan during 2018 to 2019. The data was collected from 100 diabetic patients who was suffering from diabetes from last one year. Patients from both genders, age range 35 to 65 was selected for this study. The pre devised proforma was completed by single researcher endorsing subject’s demography, and clinical profile. Fasting plasma glucose, serum TC, HDL-C, LDL-C and TG was measured by using Randox kit. Results: The data was collected from 100 patients. The demographic values shows that there is a significant relation between diabetes and hyperlipidemia in a local population of Pakistan. The value of HbA1C is 5.77 ± 0.50 in diabetic patients as compared to normal group. We found strong positive correlation between severity of DR with BSF, HbA1c, serum LDL-C, TC and TG, whereas, age and duration of DM showed moderately positive correlation with severity of diabetes. Conclusion: In our study, strong positive correlation was found between serum TC, TG, LDL-C with both BSF and HbA1c, while HDL-C showed weak negative correlation with both BSF and HbA1c