THE EFFECT OF PROBIOTIC USE ON VITAMIN D LEVELS IN OBESE CHILDREN AND ADOLESCENTS WITH VITAMIN D DEFICIENCY

According to the World Health Organization, probiotics are digestible, nonpathogenic, live microorganisms when ingested in adequate amounts as dietary components can have a beneficial effect on the host by inhibiting or treating disease (9) Obesity is defined as excess body fat and is a major health problem worldwide. The association between vitamin D deficiency and obesity and obesity-related diseases has been confirmed by a large number of studies, but the causal relationship is still unclear. Several studies have shown that the gut microbiota alters vitamin D metabolism in the gut and that probiotic supplementation may affect vitamin D levels in the blood (1-6). In this study, it was aimed to investigate the effects of adding probiotic replacement therapy to vitamin D replacement therapy on vitamin D status in obese children and adolescents with vitamin D deficiency. (1-6)