The most of the β-blockers are still clinically being sold as a racemic mixture despite the fact that their enantiomers show significant differences in the pharmacological effects and activities. This paper describes a comparative study of tow chiral separations of (RS)‐Propranolol racemate by HPLC using α-Glycoprotein (AGP) and β-Cyclodextrin (BCD) Stationary Phases. For the AGP separation, the column size was (150 mm X4 mm X 5 μm), the mobile phase composed of Propanol-2 and Ammonium acetate (0.5:99.5 v/v), at a flow rate of 0.9 mL/min and the detection by ultraviolet absorption at 225 nm. For the BCD separation, the column size was (200 mm X4 mm X 5 μm), the mobile phase composed of Acetonitrile: Ethanol: Acetic acid: Triethylamine (960:...
AbstractThe enantiomers separation of eight pharmaceutical racemates collected in Chinese Pharmacopo...
Nadolol is a nonselective beta-adrenergic receptor antagonist ( -blocker) pharmaceutical drug, widel...
Chiral chromatographic resolution of a series of dual PPARα/γ agonists was performed on the commerci...
Since the enantiomers of a number of racemic drugs have been found to have different activities or m...
The chiral separation of enantiomers is crucial for pharmacovigilance within drug discovery. Althoug...
Enantiomeric separation of the racemic metoprolol was investigated using a reverse phase HPLC (RP-HP...
Profens are known as a major group of nonsteroidal anti-inflammatory drugs, marketed as racemic mixt...
The methods for the separation of racemic compounds [(RS)-1-bromo-3-chloro-2-propanol, (RS)-1-bromo-...
Chiral separation of enantiomers of ten β-blockers is examined by using cyclodextrin-mediated capill...
Cellulose triphenylcarbamate derivatives have been used as stationary phases for resolution of the e...
Two novel chiral stationary phases (CSP 1: dimethylbutadiene and CSP 2: methylmethacylate cationic p...
High performance liquid chromatography(HPLC) has become one of the most applied techniques in the ch...
Nadolol is a pharmaceutical drug marketed as a mixture of four stereoisomers, used to treat cardiova...
Chiral separations of five β-adrenergic antagonists (propranolol, esmolol, atenolol, metoprolol, and...
The primary aim of this thesis was to successfully resolve the two enantiomers of amphetamine, R- an...
AbstractThe enantiomers separation of eight pharmaceutical racemates collected in Chinese Pharmacopo...
Nadolol is a nonselective beta-adrenergic receptor antagonist ( -blocker) pharmaceutical drug, widel...
Chiral chromatographic resolution of a series of dual PPARα/γ agonists was performed on the commerci...
Since the enantiomers of a number of racemic drugs have been found to have different activities or m...
The chiral separation of enantiomers is crucial for pharmacovigilance within drug discovery. Althoug...
Enantiomeric separation of the racemic metoprolol was investigated using a reverse phase HPLC (RP-HP...
Profens are known as a major group of nonsteroidal anti-inflammatory drugs, marketed as racemic mixt...
The methods for the separation of racemic compounds [(RS)-1-bromo-3-chloro-2-propanol, (RS)-1-bromo-...
Chiral separation of enantiomers of ten β-blockers is examined by using cyclodextrin-mediated capill...
Cellulose triphenylcarbamate derivatives have been used as stationary phases for resolution of the e...
Two novel chiral stationary phases (CSP 1: dimethylbutadiene and CSP 2: methylmethacylate cationic p...
High performance liquid chromatography(HPLC) has become one of the most applied techniques in the ch...
Nadolol is a pharmaceutical drug marketed as a mixture of four stereoisomers, used to treat cardiova...
Chiral separations of five β-adrenergic antagonists (propranolol, esmolol, atenolol, metoprolol, and...
The primary aim of this thesis was to successfully resolve the two enantiomers of amphetamine, R- an...
AbstractThe enantiomers separation of eight pharmaceutical racemates collected in Chinese Pharmacopo...
Nadolol is a nonselective beta-adrenergic receptor antagonist ( -blocker) pharmaceutical drug, widel...
Chiral chromatographic resolution of a series of dual PPARα/γ agonists was performed on the commerci...