Isolation, Structure Elucidation and Antimicrobial Studies of Aristolochic Acid from Aristolochia bracteolata Lam.

Aristolochic acid (AA I) was isolated from the dominant weed Aristolochia bracteolata Lam. Its detailed structural elucidation was obtained by sophisticated spectroscopic techniques like UV, IR, 1HNMR, HPLC, LCMS and X-RAY Crystallography. Isolated aristolochic acid was screened against the Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Aspergillus whentii, Fusarium monoliformae and Penicillum imblicatum for its biological activities. Aristolochic Acid I (AA I) is the principal constituents of Aristolochia bracteolata Lam. Antimicrobial studies led to the significant inhibitory effects against all pathogens