Precision medicine is currently an emerging approach for the treatment of childhood cancer.The use of improved molecular diagnostic techniques has facilitated the identification of actionablemolecular targets and hence additional therapeutic opportunities.Next generation sequencing (NGS) has revolutionized our understanding of pediatric cancerand fueled the personalized approach to cancer treatment.Treatment of patients with pediatric cancer is not synonymous with treatment in a mini adult. Pediatric cancers have different genetic constitution and fewer molecular targets as compared to adult tumors. This overviewdiscusses the diagnostic and therapeutic advancements alongwith some of the important clinical implications and the future prospec...
BACKGROUND:For children with cancer, the clinical integration of precision medicine to enable predic...
The implementation of personalised medicine in childhood cancers has been limited by a lack of clini...
Despite improved therapeutic and clinical outcomes for patients with localized diseases, outcomes fo...
Precision oncologic medicine is an emerging approach for cancer treatment that has recently taken gi...
Improvements in outcome have been seen in children and adolescents with cancer. Nevertheless, challe...
Over the last years, various precision medicine programs have been developed for pediatric patients ...
The maturation of genomic technologies has enabled new discoveries in disease pathogenesis as well a...
Precision oncology is defined as the selection of an effective treatment for a cancer patient based ...
Central nervous system tumors are the leading cause of cancer related death in children. Despite muc...
iTHER is a Dutch prospective national precision oncology program aiming to define tumour molecular p...
AbstractBackgroundTechnological advances including high-throughput sequencing have identified numero...
Background: Technological advances including high-throughput sequencing have identified numerous tum...
The successful implementation of precision medicine in childhood cancer care, including genomic test...
The Children’s Cancer Institute in Sydney recently launched an ambitious program. From early next ye...
The 'Individualized Therapy for Relapsed Malignancies in Childhood' (INFORM) precision medicine stud...
BACKGROUND:For children with cancer, the clinical integration of precision medicine to enable predic...
The implementation of personalised medicine in childhood cancers has been limited by a lack of clini...
Despite improved therapeutic and clinical outcomes for patients with localized diseases, outcomes fo...
Precision oncologic medicine is an emerging approach for cancer treatment that has recently taken gi...
Improvements in outcome have been seen in children and adolescents with cancer. Nevertheless, challe...
Over the last years, various precision medicine programs have been developed for pediatric patients ...
The maturation of genomic technologies has enabled new discoveries in disease pathogenesis as well a...
Precision oncology is defined as the selection of an effective treatment for a cancer patient based ...
Central nervous system tumors are the leading cause of cancer related death in children. Despite muc...
iTHER is a Dutch prospective national precision oncology program aiming to define tumour molecular p...
AbstractBackgroundTechnological advances including high-throughput sequencing have identified numero...
Background: Technological advances including high-throughput sequencing have identified numerous tum...
The successful implementation of precision medicine in childhood cancer care, including genomic test...
The Children’s Cancer Institute in Sydney recently launched an ambitious program. From early next ye...
The 'Individualized Therapy for Relapsed Malignancies in Childhood' (INFORM) precision medicine stud...
BACKGROUND:For children with cancer, the clinical integration of precision medicine to enable predic...
The implementation of personalised medicine in childhood cancers has been limited by a lack of clini...
Despite improved therapeutic and clinical outcomes for patients with localized diseases, outcomes fo...