Immuno-histochemical features of the structure of foetuses' uterine tubes from the mothers with pregnancy complications

Kupriianova Larisa. Immuno-histochemical features of the structure of foetuses' uterine tubes from the mothers with pregnancy complications. Journal of Education, Health and Sport. 2017;7(1):488-502. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.376312 http://ojs.ukw.edu.pl/index.php/johs/article/view/4314 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016). 754 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017. UDK: 618.11-053.18-091.8:618.3-06.12 Immuno-histochemical features of the structure of foetuses' uterine tubes from the mothers with pregnancy complications Larisa Kupriianova Kharkiv National Medical University Abstract Material of the research includes uterine tubes of foetuses, that were dead on the gestational term between 21 and 41 weeks. According to peculiarities in the pregnancy course this material was divided into groups: foetuses from mothers with physiological pregnancy; foetuses from mothers. whose pregnancy takes its course on the background of the PE with different stages of the severity; and, finally, foetuses from mothers, whose pregnancy was complicated by the chronic infection of lower genital tracts. Research methods: macroscopic, histological, histochemical, immunohistochemical, morphometric, statistical. It was shown an excessive proliferation of the connective tissue in all structural components, in the composition of which prevails an immature collagen of the III type. It was also increased a production of the endothelin-1 by the vascular component of organs. In addition, it was defined an oppression of the functional activity of epithelial component by mucosa, which was expressed like decreasing of the hormonal activity of the the organ and increasing of the manifestation stage of apoptosis changes. Key words: fetus, pregnancy, pre-eclampsia; infection, uterine tubes