Lacrimal activity and immunological performance in children with enterovirus uveitis

The control group consisted of 50 healthy people. The study was conducted among 150 children aged from 3 months to 14 years old with uveitis caused by enterovirus uveitis (EVU) in the population of Azerbaijan. They were divided into three groups depending on the etiology of the disease. The first group included 82 children with viral eye diseases; the second group included 42 children with viral-bacterial diseases; the third group included 26 children with viral-allergic eye diseases. One of the factors for the alternative activation of the complement system is considered to be the increase in the level of immunoglobulins of class A that leads to increased vascular permeability and the development of edema, which in turn has chemotoxic and devastating effects. In children with allergic eye changes, the IgE level increases on average by 2.2 times (p<0.05), which indicates an increase in the chemotaxis of eosinophils with eye age. As shown by the survey data, when comparing with healthy children, there is a 3.2-fold increase in the index of intoxication and aggravation of the inflammatory process in 26 sick children (p<0.05), while in 42 children allergy index is on average 2 times higher, increases are observed (p