ASSOCIATION BETWEEN OBESITY AND FATTY LIVER AMONG PATIENTS

Objective: The purpose of this case work is to find out the relationship between fatty liver & fatness among the patients appeared in Ganga Ram Hospital, Lahore, Pakistan. Methodology: This case study is a retroactive case work reviewing the clinical records of the fat patients present with fatty liver for a period of complete one year from May 2017 to April 2018. The collection of data regarding age of the patient, sex, nationality, body mass index, alanine level in serum as ALT & AST as aspartate transaminases, LDL, TSH, cholesterol, bilirubin, triglyceride, albumin & HbA1C carried for every patient. The diagnosis of the fatty liver carried out with normal routine ultrasound when most of the patients appeared with severe pain in their abdomen cavity. Results: Total two hundred and thirty five files of patients were the part of this case work. The average age of the studied population was 46.0 ± 14.40 years with 35.0% (n: 82) males & 65.0% (n: 153) females. The average level of aspartate amino-transferase was 43.90 ±6.180 units / L; the average level of alanine amino-transferase was 36.20 ± 5.10 units / L. A transaminase level of more than routine value was available in 6.40% (n: 15) patients only, while the levels of cholesterol & triglyceride above routine levels were available in 7.20% (n: 17). Fatness & obesity were very important factors of risks in the patient group of this case work. The average body mass index of the patients was 33.60 ± 7.50 Kg/m2. Diabetes mellitus with the obesity is the very vital risk factor for the presence of fatty liver. Thirty three percent (n: 78) patients of this case work were suffering from diabetes. Metabolic syndrome was another important risk factor linked with the availability of the fatty liver which is present in 14.90% & hypothyroidism was available in 3.80% patients. Conclusion: Fatness and obesity are very vital risk factors for the patients of fatty liver in our population of Pakistan. This complication is very dominating in the female sex. Ultrasound is very important tool for the determination of the fatty liver in the obese adult patients even in the non-availability of the hypertransaminasemia. There should be encouragement for the obese population to decrease their weight for the reduction in the abnormalities of the liver. KEY WORDS: Obesity, fatness, ultrasound, risk factor, methodology, metabolic syndrome, dominating, diabetes, complication