A STUDY TO FIND OUT ASSOCIATION BETWEEN BLOOD GROUP AND COMPLETE HEMOGRAM

Abstracts: Background & objectives: Numerous studies shows that certain types of diseases are more common in certain blood groups like tuberculosis is more common in type O, plasmodium vivax infection is more common in type A and O blood group. It may be possible due to genetic predisposition and immunological response in certain blood groups than others. This study also wants to find any association of hemogram parameters with various blood group types. Methods: 51 cases in time span of 1 month have been included in this study. Prior information sheet was provided to subjects about this study. On voluntary consent, subjects’ 0.5ml venous blood was collected aseptically and hemogram parameters like Hb, RBC count, PCV, MCV, MCH, MCHC, TLC and RDW-CV were measured using Auto analyser instrument. All healthy male and female subjects above 18 years were included in study. Data analysis was done by MedCalc v18.6 and single factor ANOVA was applied for various hemogram parameters. Results: Out of 51 cases, majority are A+ve and B+ve blood group with 16 cases each. O-ve and B –ve blood group types had more RBC count (4.52±0.85 & 4.52 ± 0.69 respectively) compared to other blood group types. AB+ve were found to have more TLC (9100) compared to other blood types. Interpretation & conclusion: Out of 51 cases, 47 have Rh positive and 4 are Rh negative. On applying single factor ANOVA for finding association between blood group types and RBC count, p value was found to be 0.210. Similarly for finding association between TLC and blood group types, p value was at 0.563. Thus no association was found between blood group type and TLC or RBC count. Similar findings were observed for rest of hemogram parameters