The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so called adrenal androgens. Under physiological conditions, cortisol and adrenal androgen synthesis are controlled primarily by ACTH. Although it has been established that ACTH can stimulate steroidogenesis, the effects of ACTH on overall gene expression in human adrenal cells have not been established. In this paper, we estimate the Adrenocorticotropic Hormone on cortisol and Dehydroepiandrosterone Sulfate (DHEA’s) production through Hamilton Jacobi-Bellmann equation using stochastic analysis
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Comp...
The present study aimed to characterize the adrenal response to ACTH. A model was developed that cou...
The hypothalamic-pituitary-adrenal (HPA) axis is a classic neuroendocrine system. One of the best wa...
The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so called ad...
The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so-called ad...
The literature pertaining to the modelling of the adrenal-cortical system is reviewed. Two new model...
Mathematical modeling has proven to be valuable in understanding of the complex biological systems d...
The output of estrogens, testosterone and their precursors was compared with that of glucocorticoste...
Adrenal toxicity is one of the major concerns in drug development. To quantitatively understand the ...
This is the final version of the article. Available from National Academy of Sciences via the DOI in...
This study demonstrates the application of a mathematical steroidogenic model, constructed with indi...
Adrenal steroid hormones, which regulate a plethora of physiological functions, are produced via tig...
International audienceIn the normal human adrenal gland, steroid secretion is regulated by a complex...
Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Sma...
Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Sma...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Comp...
The present study aimed to characterize the adrenal response to ACTH. A model was developed that cou...
The hypothalamic-pituitary-adrenal (HPA) axis is a classic neuroendocrine system. One of the best wa...
The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so called ad...
The adrenal glands are the primary source of minerocorticoids, glucocorticoids, and the so-called ad...
The literature pertaining to the modelling of the adrenal-cortical system is reviewed. Two new model...
Mathematical modeling has proven to be valuable in understanding of the complex biological systems d...
The output of estrogens, testosterone and their precursors was compared with that of glucocorticoste...
Adrenal toxicity is one of the major concerns in drug development. To quantitatively understand the ...
This is the final version of the article. Available from National Academy of Sciences via the DOI in...
This study demonstrates the application of a mathematical steroidogenic model, constructed with indi...
Adrenal steroid hormones, which regulate a plethora of physiological functions, are produced via tig...
International audienceIn the normal human adrenal gland, steroid secretion is regulated by a complex...
Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Sma...
Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Sma...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Comp...
The present study aimed to characterize the adrenal response to ACTH. A model was developed that cou...
The hypothalamic-pituitary-adrenal (HPA) axis is a classic neuroendocrine system. One of the best wa...