Evaluation of antibiotic susceptibility rates of non-fermentative Gram negative bacteria

Aim: One of the most important group of gram negative bacteria is non-fermenter bacteria. Non-fermenter bacteria cause hospital-related infections, especially in intensive care units. Determination of susceptibility tests of these bacteria is important for planning the empirical treatment of hospital-associated infections. In this study, we investigated the susceptibility rates of non-fermenter bacteria identified from our hospital. Materials and Methods: Antibiotic susceptibilities of non-fermenter bacteria isolated from samples coming to our laboratory from the hospital between 2010-2012 were examined. Results: A total of 156 samples were included in the study. 153 of them were isolated from patients, 3 of them were isolated from samples sent from hospital supplies. 82 of the samples were identified from the intensive care unit. Acinetobacter baumannii was the most isolated bacteria with 73. This was followed by Pseudomonas aeruginosa with 57, Stenotrophomonas maltophilia with 9. Resistance rates; For Acinetobacter baumannii: Piperacillin tazobactam (89%), cefaperazone sulbactam (67.1%), Meropenem (78%), Ciprofloxacin (86%), Tigecycline (2.7%), Colistin (1.3%), for Pseudomonas aeruginosa: Piperacillin tazobactam (10.5%), cefaperazone sulbactam (12.2%), Meropenem (8.7%), Ciprofloxacin (26.3%), Colistin (1.7%) were found. Conclusions: For each hospital, periodic evaluation of the susceptibility of the bacteria obtained from own, will strengthen the clinician's hand in empirical therapy. Tigecycline and colistin may be considered as a priority in the empirical treatment of infections where non-fermenter bacteria will be considered for our hospital