Korean Colorectal Cancer Cohort RNA-seq data set from Asan Medical Center

Colorectal cancer (CRC) is a major health concern, and understanding its molecular characteristics is crucial for improved diagnosis and treatment. In this study, we present a comprehensive analysis utilizing RNA-seq data and clinical information from Korean patients with colorectal cancer. Differential gene expression analysis identified significant gene expression changes between tumor and normal samples. Additionally, Gene Set Enrichment Analysis (GSEA) revealed dysregulated pathways associated with tumor progression. Furthermore, utilizing CMScaller, we successfully stratified colorectal cancer samples into distinct molecular subtypes. Our findings provide valuable insights into the molecular landscape of colorectal cancer in the Korean population and underscore the potential of RNA-seq data integration with clinical information for improved cancer research and patient care. The raw data and processed results of this study have been deposited in a public repository to enable further analysis and exploration. Please cite the original article