Characteristic of individual indicators of phagocytic activity of leukocytes under conditions of formation of experimental contact dermatitis and experimental pneumonia and the effect of the drug thiotriazoline

Regeda-Furdychko M. M. Characteristic of individual indicators of phagocytic activity of leukocytes under conditions of formation of experimental contact dermatitis and experimental pneumonia and the effect of the drug thiotriazoline. Journal of Education, Health and Sport. 2019;9(10):322-327. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3581338 http://ojs.ukw.edu.pl/index.php/johs/article/view/7652 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/7652 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 03.10.2019. Revised: 08.10.2019. Accepted: 30.10.2019. UDK: 616.24-002-034-11-094 Characteristic of individual indicators of phagocytic activity of leukocytes under conditions of formation of experimental contact dermatitis and experimental pneumonia and the effect of the drug thiotriazoline M. M. Regeda-Furdychko Lviv Medical Institute Abstract The work demonstrated, that polymorho-nuclear leucocytes take an active part in formation of experimental contact dermatitis and experimental pneumonia before and after administration of the antioxidant thiotriazoline and also testify to metabolic processes stimulation in leucocytes. The immune-modulating thiotriazoline preparation application, beginning from 8 th day of the experiment, and during 10 days, showed the renewal of indexes of phagocytar leucocytes' activity, the test of nitroblue tetrasolium, what testifies to its corregating action – on nonspecific resistance condition. Key words: contact dermatitis; pneumonia; polymorho-nuclear leucocytes; nonspecific resistance; thiotriazoline