DNA in bacterial cells is maintained in a negatively supercoiled state. This contributes to the organization of the bacterial nucleoid and also influences the global gene expression pattern in the cell through modulatory effects on transcription. Supercoiling arises as a result of changes to the linking number of the relaxed double-stranded DNA molecule and is set and reset by the action of DNA topoisomerases. This process is subject to a multitude of influences that are usually summarized as environmental stress. Responsiveness of linking number change to stress offers the promise of a mechanism for the wholesale adjustment of the transcription programme of the cell as the bacterium experiences different environments. Recent data from DNA ...
The effect of DNA supercoiling on transcription of a bacterial tRNA gene has been analysed in vitro ...
International audienceDNA supercoiling is an essential mechanism of bacterial chromosome compaction,...
DNA supercoiling is central to fundamental processes of living organisms. Its average level along th...
Although it has become routine to consider DNA in terms of its role as a carrier of genetic informat...
International audienceDNA supercoiling acts as a global and ancestral regulator of bacterial gene ex...
International audienceDNA supercoiling (SC), the level of under-or overwinding of the DNA polymer ar...
International audienceDNA supercoiling acts as a global transcriptional regulator in bacteria, that ...
Extended version of the ALIFE21 paper (https://hal.archives-ouvertes.fr/hal-03242696), to appear in ...
DNA supercoiling in Escherichia coli is an active process mediated by DNA gyrase. Intracellular DNA ...
Supercoiling and changes in the supercoiling state are ubiquitous in cel-lular DNA and affect virtua...
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/...
DNA of prokaryotes is in a nonequilibrium structural state, characterized as 'active' DNA supercoili...
Investigating effects of different environmental conditions on gene expression via altered global st...
The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur. The degree ...
International audienceRegulation of cellular growth implies spatiotemporally coordinated programmes ...
The effect of DNA supercoiling on transcription of a bacterial tRNA gene has been analysed in vitro ...
International audienceDNA supercoiling is an essential mechanism of bacterial chromosome compaction,...
DNA supercoiling is central to fundamental processes of living organisms. Its average level along th...
Although it has become routine to consider DNA in terms of its role as a carrier of genetic informat...
International audienceDNA supercoiling acts as a global and ancestral regulator of bacterial gene ex...
International audienceDNA supercoiling (SC), the level of under-or overwinding of the DNA polymer ar...
International audienceDNA supercoiling acts as a global transcriptional regulator in bacteria, that ...
Extended version of the ALIFE21 paper (https://hal.archives-ouvertes.fr/hal-03242696), to appear in ...
DNA supercoiling in Escherichia coli is an active process mediated by DNA gyrase. Intracellular DNA ...
Supercoiling and changes in the supercoiling state are ubiquitous in cel-lular DNA and affect virtua...
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/...
DNA of prokaryotes is in a nonequilibrium structural state, characterized as 'active' DNA supercoili...
Investigating effects of different environmental conditions on gene expression via altered global st...
The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur. The degree ...
International audienceRegulation of cellular growth implies spatiotemporally coordinated programmes ...
The effect of DNA supercoiling on transcription of a bacterial tRNA gene has been analysed in vitro ...
International audienceDNA supercoiling is an essential mechanism of bacterial chromosome compaction,...
DNA supercoiling is central to fundamental processes of living organisms. Its average level along th...