Background & Objective: Pathophysiology of Ischemia/Reperfusion (Isc/R) can cause renal and hepatic damages. Naringenin (NAR) is a flavonoid with potent antioxidant properties. In the present study, the effects of NAR on the liver after the renal Isc/R procedure were investigated. Materials & Methods: Sixty-four Wistar rats were divided into eight groups. The animals in the control group received dimethyl sulfoxide (DMSO). Group 2 as the Isc/R group went under the Isc/R procedure. Groups 3, 4, and 5 as the NAR groups received 20, 50, and 100 mg/kg of NAR, respectively. Groups 6, 7, and 8 were the Isc/R+NAR groups. The NAR was administrated for four consecutive weeks orally. Levels of the expression of p53, Bcl2, and Bax genes were assess...
Objectives: Pycnogenol® (PYC®), a standardized extract from the bark of Pinus maritima, consists of ...
Objectives: Ischemia‑reperfusion (IR) contributes to the development acute renal failure.Oxygen free...
Aims: Adrenomedullin (AM) is a multifunctional peptide with a putative beneficial role after an isch...
Background: Clinically, chronic nephrotoxicity may lead to renal functional impairment and progress ...
Objective(s): 5-FU, an anticarcinogenic agent, is reported to have side-effects that include hepatot...
Background/Aims: Hepatic injury caused by ischemia/reperfusion (I/R) is a clinical problem associate...
Vancomycin (VCM), a glycopeptide antibiotic, is a drug widely used in severe infections. However, VC...
Background and Aims: Acute hepatic injury causes systematic inflammatory responses which may finally...
Abstract Diabetes mellitus is a metabolic disorder and its incidence is considered to be high all...
Background: Ischemia/reperfusion injury (IRI) is typically associated with a vigorous inflammatory a...
European Journal of Pharmacology Volume 815, 15 November 2017, Pages 446-453Ischemia reperfusion (I...
The intestinal mucosa is known to be adversely affected by ischemia-reperfusion (I/R). It has been d...
OBJECTIVE: To investigate the effects of N-acetylcysteine (NAC) and high-dose atorvastatin (ATOR) in...
Naringenin is a natural flavonoid aglycone of naringin that has been reported to have a wide range o...
The aim of this study was to evaluate whether NAR has a hepatoprotective role in a model of STZ-indu...
Objectives: Pycnogenol® (PYC®), a standardized extract from the bark of Pinus maritima, consists of ...
Objectives: Ischemia‑reperfusion (IR) contributes to the development acute renal failure.Oxygen free...
Aims: Adrenomedullin (AM) is a multifunctional peptide with a putative beneficial role after an isch...
Background: Clinically, chronic nephrotoxicity may lead to renal functional impairment and progress ...
Objective(s): 5-FU, an anticarcinogenic agent, is reported to have side-effects that include hepatot...
Background/Aims: Hepatic injury caused by ischemia/reperfusion (I/R) is a clinical problem associate...
Vancomycin (VCM), a glycopeptide antibiotic, is a drug widely used in severe infections. However, VC...
Background and Aims: Acute hepatic injury causes systematic inflammatory responses which may finally...
Abstract Diabetes mellitus is a metabolic disorder and its incidence is considered to be high all...
Background: Ischemia/reperfusion injury (IRI) is typically associated with a vigorous inflammatory a...
European Journal of Pharmacology Volume 815, 15 November 2017, Pages 446-453Ischemia reperfusion (I...
The intestinal mucosa is known to be adversely affected by ischemia-reperfusion (I/R). It has been d...
OBJECTIVE: To investigate the effects of N-acetylcysteine (NAC) and high-dose atorvastatin (ATOR) in...
Naringenin is a natural flavonoid aglycone of naringin that has been reported to have a wide range o...
The aim of this study was to evaluate whether NAR has a hepatoprotective role in a model of STZ-indu...
Objectives: Pycnogenol® (PYC®), a standardized extract from the bark of Pinus maritima, consists of ...
Objectives: Ischemia‑reperfusion (IR) contributes to the development acute renal failure.Oxygen free...
Aims: Adrenomedullin (AM) is a multifunctional peptide with a putative beneficial role after an isch...