Major changes Added a model for epitopes Optionally, output a table with all annotated epitopes obtained from a set of input neoantigens (option --with-all-neoepitopes) Additional command line tool neofox-epitope that accepts epitopes as input. The epitopes may be associated with a particular HLA allele or alternatively paired with each of the HLA alleles defined in a given patient MHC-II weak binder threshold changed from 10 to 5 Output JSON file with reference resources metadata with the aim of documenting the reference data versions Minor changes Neoantigen model is simplified by removing the Mutation entity Annotations are renamed with the aim of making them more self explanatory Always output tabular and JSON data as opposed to choo...
Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in p...
Table S1. Top mutated genes with predicted HLA Class I binding neo-peptides in 147 lung adenocarcino...
Personalization of immunotherapies such as cancer vaccines and adoptive T cell therapy depends on id...
Neofox v0.5.0 release notes Major changes Update to NetMHCpan 4.1 Update to NetMHCIIpan 4.0 Int...
This is a minor release 0.5.2 fix of the documenation estimate features such as pathogensimilarity,...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Bugfixes Fix the documentation. Now the documentation at readthedocs is up to date Fix crash in neo...
Major Changes The annotation of neoantigen candidates from mouse are supported Uniprot instead of e...
Lack of a dedicated integrated pipeline for neoantigen discovery in mice hinders cancer immunotherap...
Neoantigens are novel peptide sequences resulting from sources such as somatic mutations in tumors. ...
abstract: Cells become cancerous due to changes in their genetic makeup. In cancers, an altered amin...
§ All non-synonymous somatic variants identified via WES translated into a 40+ character long stri...
This is a minor release that fixes a bug introduced in v0.5.2. external annotation were not added in...
Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in p...
Table S1. Top mutated genes with predicted HLA Class I binding neo-peptides in 147 lung adenocarcino...
Personalization of immunotherapies such as cancer vaccines and adoptive T cell therapy depends on id...
Neofox v0.5.0 release notes Major changes Update to NetMHCpan 4.1 Update to NetMHCIIpan 4.0 Int...
This is a minor release 0.5.2 fix of the documenation estimate features such as pathogensimilarity,...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Annotation of mutated peptide sequences (mps) with published or novel potential neo-epitope descript...
Bugfixes Fix the documentation. Now the documentation at readthedocs is up to date Fix crash in neo...
Major Changes The annotation of neoantigen candidates from mouse are supported Uniprot instead of e...
Lack of a dedicated integrated pipeline for neoantigen discovery in mice hinders cancer immunotherap...
Neoantigens are novel peptide sequences resulting from sources such as somatic mutations in tumors. ...
abstract: Cells become cancerous due to changes in their genetic makeup. In cancers, an altered amin...
§ All non-synonymous somatic variants identified via WES translated into a 40+ character long stri...
This is a minor release that fixes a bug introduced in v0.5.2. external annotation were not added in...
Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in p...
Table S1. Top mutated genes with predicted HLA Class I binding neo-peptides in 147 lung adenocarcino...
Personalization of immunotherapies such as cancer vaccines and adoptive T cell therapy depends on id...