deconstructSigs R package and README Takes sample information in the form of the fraction of mutations in each of 96 trinucleotide contexts and identifies the weighted combination of published signatures that, when summed, most closely reconstructs the mutational profile
<p>(A) After initial screening based on the ‘split mapping’ signatures (B) After removal of artifact...
Abstract Background Base substitution catalogues represent historical records of mutational processe...
Mutational signatures are patterns of mutations that arise during tumorigenesis. We present an enhan...
The mutational signature contribution to each TCGA tumor sample studied as determined by deconstruct...
Summary: Mutational signatures are patterns in the occurrence of somatic single-nucleotide vari-ants...
Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mecha...
Summary Mutational signatures are patterns in the occurrence of somatic single nucleotide variants (...
Abstract Background The somatic mutations found in a tumor have in most cases been caused by multipl...
Mutational signatures have emerged as powerful biomarkers in cancer patients, with prognostic and th...
BACKGROUND: Base substitution catalogues represent historical records of mutational processes that h...
Contains fulltext : 91858.pdf (publisher's version ) (Closed access)2011 IEEE Inte...
Funder: We thank the Human Research Tissue Bank, which is supported by the UK National Institute for...
This uploads contains the mutational signature data from the article Substitution mutational signatu...
(A) The trinucleotide contexts of significantly associated driver mutation are indicated by numberin...
Stars indicate mutations (top); red bars indicate changepoints (middle); green and purple lines indi...
<p>(A) After initial screening based on the ‘split mapping’ signatures (B) After removal of artifact...
Abstract Background Base substitution catalogues represent historical records of mutational processe...
Mutational signatures are patterns of mutations that arise during tumorigenesis. We present an enhan...
The mutational signature contribution to each TCGA tumor sample studied as determined by deconstruct...
Summary: Mutational signatures are patterns in the occurrence of somatic single-nucleotide vari-ants...
Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mecha...
Summary Mutational signatures are patterns in the occurrence of somatic single nucleotide variants (...
Abstract Background The somatic mutations found in a tumor have in most cases been caused by multipl...
Mutational signatures have emerged as powerful biomarkers in cancer patients, with prognostic and th...
BACKGROUND: Base substitution catalogues represent historical records of mutational processes that h...
Contains fulltext : 91858.pdf (publisher's version ) (Closed access)2011 IEEE Inte...
Funder: We thank the Human Research Tissue Bank, which is supported by the UK National Institute for...
This uploads contains the mutational signature data from the article Substitution mutational signatu...
(A) The trinucleotide contexts of significantly associated driver mutation are indicated by numberin...
Stars indicate mutations (top); red bars indicate changepoints (middle); green and purple lines indi...
<p>(A) After initial screening based on the ‘split mapping’ signatures (B) After removal of artifact...
Abstract Background Base substitution catalogues represent historical records of mutational processe...
Mutational signatures are patterns of mutations that arise during tumorigenesis. We present an enhan...
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