Real-time magnetic resonance imaging to study orthostatic intolerance mechanisms in human beings: Proof of concept

This dataset was acquired at DLR, Cologne, Germany. The study complied with the Declaration of Helsinki, and was approved by the local ethics committee. All subjects gave written informed consent. Data acquisition MRI data All MR images were acquired on a Siemens 3T mMR Biograph using cardiac, spine and head coils. The scanning protocol consisted of the following sequences. MPI70_SA20_FOV320_16X6MM_33MS: cardiac real-time MRI of the short axis (TR=2.56 ms; TE=1.62 ms; FA= 10°; 1.6x1.6 mm; 6 mm slice thickness; 20 slices; FoV320x320 mm; radial spokes 13) MPI70_TP_PCMV100_FOV320_15X6MM_33MS: blood flow real-time MRI of the pulmonary trunk (TR=3.33 ms; TE=2.24 ms; FA= 10°; 1.5x1.5 mm; 6 mm slice thickness; FoV=320x320 mm; VENC=100 cm/s; radial spokes 5) MPI70_PCMV100_FOV192_075X6MM_80MS: blood flow real-time MRI of the middle cerebral artery (TR=4.44 ms; TE=3.10 ms; FA= 12°; 0.75x0.75 mm; 6 mm slice thickness; FoV=192x192 mm; VENC=100 cm/s; radial spokes 9) Cinematic real-time MRI of the short axis view and blood flow measurements of the pulmonary trunk and in the left and right middle cerebral artery were acquired at baseline and during -30mmHg LBNP. Video files: https://zenodo.org/record/7066642/files/Series_040_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=1 https://zenodo.org/record/7066642/files/Series_103_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=